Journal ArticleDOI
A Simple, Efficient and Green Procedure for the Knoevenagel Condensation of Aldehydes with N-Methylpiperazine at Room Temperature under Solvent-Free Conditions
Chhanda Mukhopadhyay,Arup Datta +1 more
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TLDR
In this article, Knoevenagel condensation of aromatic, aliphatic, and heteroaromatic aldehydes with active methylene compounds such as ethylcyanoacetate, malononitrile, and cyanoacetamide proceed very smoothly at room temperature by simply mixing the ingredients together under solvent-free conditions.About:
This article is published in Synthetic Communications.The article was published on 2008-08-18. It has received 35 citations till now. The article focuses on the topics: Knoevenagel condensation & Malononitrile.read more
Citations
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Journal ArticleDOI
Efficient and reusable amine-functionalized polyacrylonitrile fiber catalysts for Knoevenagel condensation in water
Guowei Li,Jia Xiao,Wenqin Zhang +2 more
TL;DR: A series of new fiber catalysts has been synthesized by aminating a commercially available polyacrylonitrile fiber with polyamines such as diethylenetriamine and triethylenetetramine as discussed by the authors.
Journal ArticleDOI
Rapid and efficient Knoevenagel condensation catalyzed by a novel protic ionic liquid under ultrasonic irradiation
TL;DR: An efficient and reusable protic-ionic-liquid solvent-catalyst system, HMTA-AcOH-H2O, has been developed and used in the Knoevenagel condensation reaction of aromatic aldehydes with ethyl 2-cyanoacetate as discussed by the authors.
Journal ArticleDOI
Synthesis of 3-(2-furylmethylene)-2,4-pentanedione using DL-Alanine functionalized MCM-41 catalyst via Knoevenagel condensation reaction
TL;DR: In this article, an alanine functionalized MCM-41 (Alanine-MCM41) was used as a solid base catalysts for the Knoevenagel condensation of furfural and acetylacetone under solvent free condition.
Journal ArticleDOI
Green and efficient Knoevenagel condensation catalysed by a DBU based ionic liquid in water
TL;DR: An efficient and facile protocol for the Knoevenagel condensation of aromatic aldehydes with active methylene compounds with task specific ionic liquid 1,8-diazabicyclo[5.4.0]-undec-... was proposed in this paper.
Journal ArticleDOI
A new silica based substituted piperidine derivative catalyzed expeditious room temperature synthesis of homo and hetero bis-Knoevenagel condensation products
Chhanda Mukhopadhyay,Suman Ray +1 more
TL;DR: In this paper, a new silica based piperidine derivative has been designed, synthesized and characterized by solid state carbon 13 CP MAS NMR, BET surface area analysis, IR, TGA studies, elemental analysis and pH experiment.
References
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Journal ArticleDOI
Knoevenagel condensation in the heterogeneous phase using aluminum phosphate-aluminum oxide as a new catalyst
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Uncatalysed Knoevenagel condensation in aqueous medium at room temperature
Mohit L. Deb,Pulak J. Bhuyan +1 more
TL;DR: In this article, the condensation of various aromatic and heteroaromatic aldehydes with active methylene compounds like malononitrile, e.g., barbituric acids, Meldrum's acid, dimedone and pyrazolone is described.
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Silica gel functionalized with amino groups as a new catalyst for Knoevenagel condensation under heterogeneous catalysis conditions
TL;DR: In this article, the authors show that the catalytic support is recoverable without regeneration, and that the matrix probably participates to the catalysis mechanism, and they also show that koevenagel condensation is possible without regeneration.
Journal ArticleDOI
Calcite and fluorite as catalyst for the Knövenagel condensation of malononitrile and methyl cyanoacetate under solvent-free conditions
Shinobu Wada,Hitomi Suzuki +1 more
TL;DR: When milled together with calcite or fluorite, malononitrile and methyl cyanoacetate readily underwent Knovenagel condensation with aromatic aldehydes, giving the corresponding arylidenemalononitriles and (E)-α-cyanocinnamic esters in good yield as mentioned in this paper.
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Search for a simpler synthetic model system for intramolecular 1,3-dipolar cycloaddition to the 5,6-double bond of a pyrimidine nucleoside
TL;DR: In this article, a simpler model system for the study of intramolecular thermal reactions between the base and 5'-functionalized sugar moiety in nucleosides was proposed.
Related Papers (5)
Ionic Liquid as Catalyst and Reaction Medium – A Simple, Efficient and Green Procedure for Knoevenagel Condensation of Aliphatic and Aromatic Carbonyl Compounds Using a Task‐Specific Basic Ionic Liquid
Brindaban C. Ranu,Ranjan Jana +1 more