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Book ChapterDOI

A Study of Mechanical Behavior of an Encapsulated Stent Design Using Finite Element Analysis

TL;DR: This study develops a peripheral vascular endovascular stent-graft for the treatment of various pathologies that affect peripheral vasculature, in particular, femeropopliteal arterial disease.
Abstract: Aim: Peripheral vasculature of the human body includes the blood vessels that supply the extremities and the major vessels that supply the brain. Major peripheral vascular pathologies that affect the peripheral vasculature are arterial occlusive disease or stenosis (vessel narrowing), aneurysms (vessel enlargement) and various types of trauma. The aim of this study was to develop a peripheral vascular endovascular stent-graft for the treatment of various pathologies that affect peripheral vasculature, in particular, femeropopliteal arterial disease. The stent graft is composed of a nitinol framework covered by a polymeric tube.
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Journal ArticleDOI
TL;DR: The goals of this new consensus are to provide an abbreviated document to focus on key aspects of diagnosis and management, and to update the information based on new publications and the newer guidelines, but not to add an extensive list of references.

7,099 citations

Journal ArticleDOI
TL;DR: Stent placement and PTA yielded similar complication rates, but the technical success rate was higher after stent placements and the risk of long-term failure was reduced.
Abstract: PURPOSE: To estimate and compare the results of percutaneous transluminal angioplasty (PTA) and stent placement to treat aortoiliac occlusive disease. MATERIALS AND METHODS: A meta-analysis was performed of data in six PTA studies (1,300 patients) and eight stent placement studies (816 patients) published in 1990 or later that met the inclusion criteria. Proportions were combined by means of a random-effects model. Failure-time data were pooled with and pooled without adjustment for differences in case mix. RESULTS: The immediate technical success rate in the PTA group was 91%; the rate was higher in the stent group (96%), but the difference was not statistically significant [corrected]. Complication and mortality rates were not statistically significantly different. Analyzed data included technical failures and were adjusted for lesion type and disease severity. Four-year primary patency rates were 65% for stenoses versus 54% for occlusions after PTA to treat claudication and were 53% for stenoses versus...

416 citations

Journal ArticleDOI
TL;DR: Patients with critical rest limb ischemia or severe progressive claudication need to be treated with revascularization to minimize the chance of limb loss, reduce symptoms, and improve quality of life.
Abstract: Peripheral arterial disease (PAD) is part of a global vascular problem of diffuse atherosclerosis. PAD patients die mostly of cardiac and cerebrovascular-related events and much less frequently due to obstructive disease of the lower extremities. Aggressive risk factors modi. cation is needed to reduce cardiac mortality in PAD patients. These include smoking cessation, reduction of blood pressure to current guidelines, aggressive low density lipoprotein lowering, losing weight, controlling diabetes and the use of oral antiplatelet drugs such as aspirin or clopidogrel. In addition to quitting smoking and exercise, cilostazol and statins have been shown to reduce claudication in patients with PAD. Patients with critical rest limb ischemia or severe progressive claudication need to be treated with revascularization to minimize the chance of limb loss, reduce symptoms, and improve quality of life.

274 citations