A systematic review of tests to predict cerebral palsy in young children.
Citations
744 citations
Cites result from "A systematic review of tests to pre..."
...High-quality evidence also indicates that a trajectory of abnormal GMs or HINE scores, in combination with abnormal MRI, producing congruent findings, is even more accurate than individual clinical assessments in isolation.(21,25)...
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175 citations
Cites background from "A systematic review of tests to pre..."
...The facts Substantial risks for cerebral palsy existed in the medical history: multiple birth, extreme prematurity, male gender, feeding issues, and prolonged hospitalization(14) The General Movements assessment has the best sensitivity of all tools for detecting cerebral palsy early (98% sensitivity and 91% specificity at 10-20 weeks post term age; versus gold standard MRI with 80%-87% sensitivity; versus neurologic examination with 57%-86% sensitivity in preterms and 68%-96% sensitivity post-term age).(17,18) 12%-20% of children with cerebral palsy will have normal neuroimaging and neuroimaging should not be used in isolation....
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152 citations
Cites background from "A systematic review of tests to pre..."
...GMA is non-invasive, even non-intrusive, cost-efficient, and easy to learn within three to five days of training.3,5 Bosanquet et al.13 recently compared different structural and functional assessments used for early identification of CP risk and found that GMA had the best predictive power and…...
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146 citations
Cites background or methods from "A systematic review of tests to pre..."
...Meta-analysis of six studies including over 2400 preterm infants on the power of neonatal cUS to predict CP indicated an estimated sensitivity of 74% and an estimated specificity of 92% (77)....
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...However, existing data suggest that high sensitivity and high specificity (38, 77)....
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...However, calculation of predictive values for CP is precluded due to the limited data on prediction available, or due to the fact that studies evaluating the predictive properties used more global “abnormality” outcomes (77, 85, 92)....
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...When a single assessment is used, prediction is best when GMA is carried around 3 months post-term [median sensitivity 98% (range 50–100%), specificity 94% (range 35–100%) (77, 85, 86)]....
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...Predictive validity of these assessments is generally good (82), with an estimated sensitivity and specificity for CP of 88–92%, respectively (77)....
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141 citations
References
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"A systematic review of tests to pre..." refers methods in this paper
...Study validity was analysed using the Standards for Reporting Diagnostic Accuracy (STARD) criteria with added specific questions for this review (Appendix SIIa, online supporting information).(27) Demographic variables collected included median and range of gestational age, birthweight, sex, age at diagnosis, age at confirmed diagnosis, classification and distribution of CP, identified differential diagnosis, and how differential diagnoses were handled (Table I and Table SI, online supporting information)....
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1,309 citations
"A systematic review of tests to pre..." refers methods in this paper
...To be included, studies needed to confirm a diagnosis of CP after the age of 2 years, when motor function is considered more stable and myelination is largely complete.(25) As males are known to be at higher risk of CP (accounting for 55% of the total population),(26) a sex bias of 30% towards males was allowed for....
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