Journal ArticleDOI
A systematic review of variables associated with the relationship between obesity and depression.
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TLDR
Improved understanding of this relationship will inform identification, prevention and intervention efforts, and can inform future research examining moderators, mediators and mechanisms of the relationship between obesity and depression.Abstract:
Summary
Obesity is one of the leading causes of preventable diseases and disability worldwide, and depression is among the leading causes of burden of disease. Both disorders are increasingly prevalent and comorbid. This comorbidity compounds associated health. While there is consistent evidence of a bidirectional obesity depression relationship, little is known about the biopsychosocial variables associated with this relationship. A systematic review was undertaken to identify variables associated with the relationship between obesity (Body mass index > 30 kg m−2) and depression. Forty-six studies were identified. Obesity, educational attainment, body image, binge eating, physical health, psychological characteristics and interpersonal effectiveness were consistently associated with the relationship between obesity and depression. The current review identified potential biopsychosocial variables associated with the relationship between obesity and depression. This knowledge can inform future research examining moderators, mediators and mechanisms of the relationship between obesity and depression. Improved understanding of this relationship will inform identification, prevention and intervention efforts.read more
Citations
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Exercise therapy improves both mental and physical health in patients with major depression
TL;DR: Clinical guidelines for exercise therapy in depressed patients derived from recent meta-analyses are presented, warning physical therapists that several characteristics of major depression and physical health problems interfere with participation in exercise.
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Stigma and the perpetuation of obesity
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The biology of Nociceptin/Orphanin FQ (N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence.
Jeffrey M. Witkin,Michael A. Statnick,Linda M. Rorick-Kehn,John E. Pintar,Michael Ansonoff,Yanyun Chen,R. Craig Tucker,Roberto Ciccocioppo +7 more
TL;DR: Critical evaluation of the current scientific preclinical literature suggests that small molecule modulators of nociceptin opioid peptide receptors (NOP) might be useful in the treatment of diseases related to these biological functions and that antagonism of NOP receptors will produce anti-obesity and antidepressant activities in humans.
Clinical Problems Caused by Obesity
TL;DR: Over the past few decades the incidence of obesity has doubled worldwide and current estimates classify more than 1.5 billion adults as overweight and at least 500 million of them as clinically obese, with body mass index (BMI) over 25 kg/m2 and 30 kg/ m2, respectively.
References
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Journal ArticleDOI
Depression, chronic diseases, and decrements in health: results from the World Health Surveys
TL;DR: Depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes, and the urgency of addressing depression as a public-health priority is indicated to improve the overall health of populations.
Journal Article
Depression, chronic diseases, and decrements in health : results from the world health surveys. Commentary
TL;DR: In this paper, the authors explored the effect of depression, alone or as a comorbidity, on overall health status and found that depression produces the greatest decrement in health compared with the chronic diseases angina, arthritis, asthma, and diabetes.