Journal ArticleDOI
A Theoretical Study of Epidural Electrical Stimulation of the Spinal Cord Part I: Finite Element Analysis of Stimulus Fields
Barry Coburn,Wing Kee Sin +1 more
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This first paper, of two, describes a three-dimensional finite element computer model representing nonhomogeneous electrical conductivity of the human thorax, taking account of various tissue types and other biological materials.Abstract:
This first paper, of two, describes a three-dimensional finite element computer model representing nonhomogeneous electrical conductivity of the human thorax. The spinal canal is treated in detail, taking account of various tissue types and other biological materials. Solutions are presented for the electrical fields generated within the spinal cord from bipolar epidural electrodes. Included in an Appendix is a validation study which compares experimental data in the literature, for subdural electrode arrays in a monkey, to theoretical solutions following the same method as the main work.read more
Citations
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Hindlimb stepping movements in complete spinal rats induced by epidural spinal cord stimulation.
Ronaldo M. Ichiyama,Yu.P. Gerasimenko,Yu.P. Gerasimenko,Hui Zhong,Roland R. Roy,V. R. Edgerton +5 more
TL;DR: The rat spinal cord isolated from brain control is capable of producing bilateral stepping patterns induced most readily by epidural stimulation applied at the L2 spinal segment, which were dependent on sensory feedback associated with weight bearing.
Journal ArticleDOI
Spinal cord stimulation electrode design: prospective, randomized, controlled trial comparing percutaneous and laminectomy electrodes-part I: technical outcomes.
TL;DR: It is immediately infer from technical data that the use of an insulated array, in comparison with a percutaneous electrode, would double battery life and be associated with improved clinical outcomes.
Journal ArticleDOI
Recruitment of dorsal column fibers in spinal cord stimulation: influence of collateral branching
TL;DR: It was found that transmembrane potentials, due to external monopolar stimulation, at the node at which a collateral is attached, is significantly influenced by the presence of the collateral.
Journal ArticleDOI
Epidural electrical stimulation of posterior structures of the human lumbosacral cord: 2. quantitative analysis by computer modeling.
TL;DR: Simulation of the computed recruitment order of an ensemble of ventral and dorsal root fibers shows a strong relation between electrode position and the order of muscle twitches which is based on the segmental arrangement of innervation of lower limb muscles.
Journal ArticleDOI
Stimulation of the Human Lumbar Spinal Cord With Implanted and Surface Electrodes: A Computer Simulation Study
TL;DR: Computer modeling is applied to compare the depolarization of posterior root fibers by both stimulation techniques to provide a biophysical explanation for the electrophysiological findings of lower limb muscle responses induced by posterior root stimulation.
References
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Journal ArticleDOI
The specific resistance of biological material—A compendium of data for the biomedical engineer and physiologist
L. A. Geddes,L. E. Baker +1 more
TL;DR: The paper traces the history of, and tabulates determinations of the electrical resistivity of blood, other body fluids, cardiac muscle, skeletal muscle, lung, kidney, liver, spleen, pancreas, nervous tissue, fat, bone, and other miscellaneous tissues.
Journal ArticleDOI
Electrical inhibition of pain by stimulation of the dorsal columns: preliminary clinical report.
TL;DR: Electrical Inhibition of Pain by Stimulation of the Dorsal Columns: Preliminary Clinical Report
Journal ArticleDOI
The conductivity of living tissues.
Herman P. Schwan,C. F. Kay +1 more
TL;DR: Investigation of the homogeneity of the electrical properties of tissue is indicated, and data that characterize the passive electrical characteristics of tissue as existent for the currents generated by the heart are reported.
Journal Article
Chronic dorsal column stimulation in multiple sclerosis. Preliminary report.
A W Cook,S P Weinstein +1 more
Journal ArticleDOI
Spinal cord stimulation in multiple sclerosis: clinical results.
TL;DR: Clinical results of spinal cord stimulation by means of epidural electrodes are reported in 19 patients with multiple sclerosis, indicating that the response is not caused either by a placebo effect or by the natural fluctuation of the disease.