Journal ArticleDOI
A ''turn-off'' SERS-based detection platform for ultrasensitive detection of thrombin based on enzymatic assays
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TLDR
A novel "turn-off" SERS biosensor for thrombin detection based on enzymatic amplification is established with sensitivity, selectivity and simplicity as AuNPs and peptides are easily accessible.About:
This article is published in Biosensors and Bioelectronics.The article was published on 2013-06-15. It has received 69 citations till now.read more
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SERS-Activated Platforms for Immunoassay: Probes, Encoding Methods, and Applications
TL;DR: Focusing on several basic elements in SERS immunoassays, typical structures of SERS nanoprobes, productive optical spectral encoding strategies, and popular immunoASSay platforms are highlighted, followed by their representative biological applications in the last 5 years.
Journal ArticleDOI
A SERS-based lateral flow assay biosensor for highly sensitive detection of HIV-1 DNA
TL;DR: The proposed SERS-based lateral flow assay to quantitatively detect a broad range of genetic diseases with high sensitivity is demonstrated, and human immunodeficiency virus type 1 (HIV-1) DNA was chosen as the specific biomarker.
Journal ArticleDOI
Peptide-based biosensors.
TL;DR: Progress on immobilization and microarray techniques of peptides has facilitated the progress and commercial application of chip-based peptide biosensors in clinical diagnosis, and peptides may play a generalist role in peptide-based bios Sensors.
Journal ArticleDOI
Nanotechnology-Enhanced No-Wash Biosensors for in Vitro Diagnostics of Cancer.
TL;DR: This review provides a comprehensive overview of various nanomaterial-enhanced no-wash biosensing technologies and focuses on the analysis of the underlying mechanism of these technologies applied for the early detection of cancer biomarkers ranging from small molecules to proteins, and even whole cancerous cells.
Journal ArticleDOI
Nanomaterials for Ultrasensitive Protein Detection
TL;DR: A series of nanomaterials including nanoparticles, nanofibers, nanowires, and nanosheets are reviewed, and their performances in the application for protein detection are evaluated, focusing on approaches that realize ultrasensitive detection.
References
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Journal ArticleDOI
Probing Single Molecules and Single Nanoparticles by Surface-Enhanced Raman Scattering
Shuming Nie,Steven R. Emory +1 more
TL;DR: In this article, surface-enhanced Raman scattering was used to detect single molecules and single nanoparticles at room temperature with the use of surface enhanced Raman, and the intrinsic Raman enhancement factors were on the order of 10 14 to 10 15, much larger than the ensemble-averaged values derived from conventional measurements.
Journal ArticleDOI
Preparation of aptamer-linked gold nanoparticle purple aggregates for colorimetric sensing of analytes
Juewen Liu,Yi Lu +1 more
TL;DR: A protocol for the preparation of aptamer-linked gold nanoparticle purple aggregates that undergo fast disassembly into red dispersed nanoparticles upon binding of target analytes is described, which has proved to be generally applicable for colorimetric sensing of a broad range of analytes.
Journal ArticleDOI
Characterization of the Surface of a Citrate-Reduced Colloid Optimized for Use as a Substrate for Surface-Enhanced Resonance Raman Scattering
TL;DR: In this article, an optimized procedure for the reduction of silver nitrate with trisodium citrate is described, and a robust method for surface-enhanced Raman scattering (SE(R)RS) analysis at the surface is developed.
Journal ArticleDOI
Size Correlation of Optical and Spectroscopic Properties for Gold Nanoparticles
Peter N. Njoki,I. Im S. Lim,Derrick Mott,Hye Young Park,Bilal Ahmad Khan,Suprav Mishra,Ravishanker Sujakumar,Jin Luo,Chuan-Jian Zhong +8 more
TL;DR: In this paper, a correlation of the particle size with the surface plasmon (SP) resonance band properties and the surface-enhanced Raman scattering (SERS) spectroscopic properties was found for nanoparticles with diameters ranging from 10 to 100 nm in aqueous solutions.
Journal ArticleDOI
Shell Thickness-Dependent Raman Enhancement for Rapid Identification and Detection of Pesticide Residues at Fruit Peels
Bianhua Liu,Guangmei Han,Guangmei Han,Zhongping Zhang,Renyong Liu,Changlong Jiang,Suhua Wang,Ming-Yong Han,Ming-Yong Han +8 more
TL;DR: The shell thickness-dependent Raman enhancement of silver-coated gold nanoparticles (Au@Ag NPs) for the identification and detection of pesticide residues at various fruit peels is reported.
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