Accumulation of deficits as a proxy measure of aging.
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5,456 citations
2,149 citations
Cites background or methods or result from "Accumulation of deficits as a proxy..."
...67) [5,6,8]; and 4) Association of the mean value of the Frailty Index with mortality [4-6,8,10,25]....
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...03 per year) [4-6]; 3) The presence of a sub-maximal, age-invariant limit to the Frailty Index (prior estimate is ~0....
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...Although the idea and approach are relatively simple, the results yielded by the frailty index have been consistent between surveys evaluated by our group [4-7] and by others [8-11] even though not every frailty index considers the same deficits, or even the same number of deficits....
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...the distribution, the slope and limit of deficit accumulation) of each Frailty Index were provided so that they maybe used, as in previous papers [4-11], to describe the overall frailty state of the group....
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...The two calculated indexes, one from baseline and one at follow-up, were compared with previously published indexes, to see how well each fit the following characteristics: 1) The Frailty Index should have a skewed density distribution (histogram) that is well approximated by a gamma distribution [4,8,10] 2) The rate of deficit accumulation (prior estimate is 0....
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1,998 citations
Cites background from "Accumulation of deficits as a proxy..."
...Instead, the frailty index can be considered as a state variable, in that it characterizes the whole health of individuals and validly classifies risk across a wide range of people (7,46)....
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1,254 citations
Cites background from "Accumulation of deficits as a proxy..."
...of deficits accumulated over time, termed frailty index (FI), including disability, diseases, physical and cognitive impairments, psychosocial risk factors, and geriatric syndromes (eg, falls, delirium, and urinary incontinence).(7) Compared with the Fried...
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1,075 citations
References
9,803 citations
"Accumulation of deficits as a proxy..." refers methods in this paper
...) often used for the modeling of the systems failure in the reliability theory applications and survival analysis[11-13]....
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4,656 citations
"Accumulation of deficits as a proxy..." refers background in this paper
...Redundancy in relation to reliability and aging has been thoroughly discussed[12] and likely also reflects the earlier concept of the reliable system arising from nonreliable elements[16,17]....
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...Our finding that the proportion of deficits influences life expectancy is consistent with vulnerability in any complex system arising due to loss of interconnectedness of the part[15-18]....
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4,600 citations
"Accumulation of deficits as a proxy..." refers methods in this paper
...) often used for the modeling of the systems failure in the reliability theory applications and survival analysis[11-13]....
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2,536 citations
"Accumulation of deficits as a proxy..." refers methods in this paper
...The sample was representative of elderly Canadians, and was screened using a standard cognitive test[9]....
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2,271 citations