Journal ArticleDOI
ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries
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TLDR
The evaluation of hepatocellular injury includes testing for viral hepatitis A, B, and C, assessment for nonalcoholic fatty liver disease and alcoholic liver disease, screening for hereditary hemochromatosis, autoimmune hepatitis, Wilson’s disease, and alpha-1 antitrypsin deficiency.About:
This article is published in The American Journal of Gastroenterology.The article was published on 2017-01-01. It has received 603 citations till now. The article focuses on the topics: Liver function tests & Liver biopsy.read more
Citations
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A longitudinal big data approach for precision health
Sophia Miryam Schüssler-Fiorenza Rose,Sophia Miryam Schüssler-Fiorenza Rose,Kévin Contrepois,Kegan J. Moneghetti,Kegan J. Moneghetti,Kegan J. Moneghetti,Wenyu Zhou,Tejaswini Mishra,Samson Mataraso,Orit Dagan-Rosenfeld,Ariel B. Ganz,Jessilyn Dunn,Daniel Hornburg,Shannon Rego,Dalia Perelman,Sara Ahadi,M. Reza Sailani,Yanjiao Zhou,Shana R. Leopold,Jieming Chen,Melanie Ashland,Jeffrey W. Christle,Jeffrey W. Christle,Monika Avina,Patricia Limcaoco,Camilo Ruiz,Marilyn Tan,Atul J. Butte,George M. Weinstock,George M. Slavich,Erica Sodergren,Tracey McLaughlin,Francois Haddad,Francois Haddad,Michael Snyder,Michael Snyder +35 more
TL;DR: The ability of deep longitudinal profiling to make health-related discoveries, identify clinically relevant molecular pathways and affect behavior in a prospective longitudinal cohort enriched for risk of type 2 diabetes mellitus is explored.
Journal ArticleDOI
Guidelines on the management of abnormal liver blood tests
Philip N. Newsome,R Cramb,Suzanne Davison,John F. Dillon,Mark Foulerton,Edmund Godfrey,Richard Hall,Ulrike Harrower,Mark Hudson,Andrew Langford,Anne Mackie,Robert Mitchell-Thain,Karen Sennett,Nick Sheron,Julia Verne,Martine Walmsley,Andrew Yeoman +16 more
TL;DR: These updated guidelines on the management of abnormal liver blood tests have been commissioned by the Clinical Services and Standards Committee (CSSC) of the British Society of Gastroenterology (BSG) under the auspices of the liver section of the BSG.
Journal ArticleDOI
American Association of Clinical Endocrinology Clinical Practice Guideline for the Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Primary Care and Endocrinology Clinical Settings: Co-Sponsored by the American Association for the Study of Liver Diseases (AASLD).
Kenneth Cusi,Scott D. Isaacs,Diana Barb,Rita Basu,Sonia Caprio,W. Timothy Garvey,Sangeeta R. Kashyap,Jeffrey I. Mechanick,Marialena Mouzaki,Karl Nadolsky,Mary E. Rinella,Miriam B. Vos,Zobair M. Younossi +12 more
TL;DR: A task force of medical experts developed evidence-based guideline recommendations based on a review of clinical evidence, expertise, and informal consensus, according to established American Association of Clinical Endocrinology protocol for guideline development as discussed by the authors .
Journal ArticleDOI
Epidemiology, Presentation, and Diagnosis of Celiac Disease
TL;DR: If proven accurate and scalable, assays that detect gluten-HLA tetramer complexes might be used in diagnosis to be made in the context of a gluten-free diet, without intestinal biopsy.
Journal ArticleDOI
Serum calcium as a biomarker of clinical severity and prognosis in patients with coronavirus disease 2019.
Jia-Kui Sun,Jia-Kui Sun,Wen-Hao Zhang,Wen-Hao Zhang,Lei Zou,Lei Zou,Ying Liu,Ying Liu,Jing-Jing Li,Xiao-Hua Kan,Xiao-Hua Kan,Lian Dai,Lian Dai,Qian-Kun Shi,Qian-Kun Shi,Shou-Tao Yuan,Shou-Tao Yuan,Wenkui Yu,Wenkui Yu,Hong-Yang Xu,Hong-Yang Xu,Wei Gu,Wei Gu,Jian-Wei Qi,Jian-Wei Qi +24 more
TL;DR: Serum calcium was associated with the clinical severity and prognosis of patients with COVID-19 and Hypocalcemia may be associated with imbalanced VD and PTH levels.
References
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GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Gordon H. Guyatt,Andrew D Oxman,Gunn Elisabeth Vist,Regina Kunz,Yngve Falck-Ytter,Pablo Alonso-Coello,Holger J. Schünemann +6 more
TL;DR: The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.
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Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity
Jeffrey D. Browning,Lidia S. Szczepaniak,Robert L. Dobbins,Pamela Nuremberg,Jay D. Horton,Jonathan Cohen,Scott M. Grundy,Helen H. Hobbs +7 more
TL;DR: The prevalence of hepatic steatosis was greater in men than women among whites, but not in blacks or Hispanics, and significant ethnic and sex differences in the prevalence may have a profound impact on susceptibility to Steatosis‐related liver disease.
Journal ArticleDOI
The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association
Naga Chalasani,Zobair M. Younossi,Joel E. Lavine,Anna Mae Diehl,Elizabeth M. Brunt,Kenneth Cusi,Michael Charlton,Arun J. Sanyal +7 more
TL;DR: This is a practice guideline for clinicians rather than a review article and interested readers can refer to several comprehensive reviews published recently.
Journal ArticleDOI
Chronic hepatitis B: Update 2009
Anna S.F. Lok,Brian J. McMahon +1 more
TL;DR: The 2009 update of the American Association for the Study of Liver Diseases (AASLD) Practice Guidelines for Management of Chronic Hepatitis B is now posted online at www.aasld.org, and the recommendation for first-line oral antiviral medications has been changed to tenofovir or entecavir, and adefovir has been moved to second-line Oral antiviral medication.
Journal ArticleDOI
Transaminase activity in human blood
TL;DR: To determine if transaminase activity could be demonstrated in human serum and blood cellular elements and, if so, to study any variations in activity of this enzyme in the blood of normal and diseased man.