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Journal ArticleDOI

Acute Brain Failure: Pathophysiology, Diagnosis, Management, and Sequelae of Delirium

José R. Maldonado
- 01 Jul 2017 - 
- Vol. 33, Iss: 3, pp 461-519
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TLDR
The epidemiology, known etiological factors, presentation and characteristics, prevention, management, and impact of delirium are discussed.
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This article is published in Critical Care Clinics.The article was published on 2017-07-01. It has received 201 citations till now. The article focuses on the topics: Delirium & Acute care.

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Citations
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Journal ArticleDOI

Delirium pathophysiology: An updated hypothesis of the etiology of acute brain failure.

TL;DR: Delirium is the most common neuropsychiatric syndrome encountered by clinicians dealing with older adults and the medically ill and is best characterized by 5 core domains: cognitive deficits, attentional deficits, circadian rhythm dysregulation, emotional Dysregulation, and alteration in psychomotor functioning.
Journal ArticleDOI

Clinical Assessment and Management of Delirium in the Palliative Care Setting

TL;DR: Until recently, antipsychotics have played a pivotal role in delirium management, but this role now requires critical re-evaluation in light of recent research that failed to demonstrate their efficacy in mild- to moderate-severity deliria occurring in palliative care patients.

Efficacy and safety of haloperidol versus atypical antipsychotic medications in the treatment of delirium

TL;DR: Haloperidol, risperidone, olanzapine, and quetiapine were equally efficacious and safe in the treatment of delirium, however, age is a factor that needs to be considered when making a choice of antipsychotic medication for the Treatment of Delirium.
Journal ArticleDOI

Applying machine learning to continuously monitored physiological data.

TL;DR: This commentary reviews published and potential applications for the use of ML for monitoring within the hospital environment and presents use cases as well as several questions regarding the application of ML to the analysis of the vast amount of complex data that clinicians must interpret in the realm of continuous physiological monitoring.
References
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Journal ArticleDOI

A short portable mental status questionnaire for the assessment of organic brain deficit in elderly patients

TL;DR: A 10‐item Short Portable Mental Status Questionnaire (SPMSQ), easily administered by any clinician in the office or in a hospital, has been designed, tested, standardized and validated.
Journal ArticleDOI

Clarifying Confusion: The Confusion Assessment Method: A New Method for Detection of Delirium

TL;DR: The CAM is sensitive, specific, reliable, and easy to use for identification of delirium and was shown to have convergent agreement with four other mental status tests, including the Mini-Mental State Examination.
Journal ArticleDOI

Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit

TL;DR: Delirium was an independent predictor of higher 6-month mortality and longer hospital stay even after adjusting for relevant covariates including coma, sedatives, and analgesics in patients receiving mechanical ventilation.
Journal ArticleDOI

Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial.

TL;DR: A strategy for whole-body rehabilitation-consisting of interruption of sedation and physical and occupational therapy in the earliest days of critical illness-was safe and well tolerated, and resulted in better functional outcomes at hospital discharge, a shorter duration of delirium, and more ventilator-free days compared with standard care.
Related Papers (5)

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