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Adult eczema prevalence and associations with asthma and other health and demographic factors: A US population–based study

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TLDR
The results suggest multiple demographic and socioeconomic influences on the US prevalence of adult eczema may be influenced by Hispanic ethnicity, US birthplace, and higher level of household education.
Abstract
Background Little is known about the epidemiology of eczema in adults. The goal of this study was to determine the prevalence of and associations with adult eczema in the United States. Methods We used the 2010 National Health Interview Survey from a nationally representative sample of 27,157 adults age 18 to 85 years. Results Overall, the 1-year prevalence of eczema was 10.2% (95% CI, 9.7% to 10.6%). The 1-year prevalence of eczema with asthma and/or hay fever was 3.2% (95% CI, 2.8% to 3.3%). Adult eczema was associated with higher prevalence of asthma ( P 2 test), more asthma attacks in the past year ( P P  = .02). In multivariate models eczema prevalence was significantly higher in older participants; female subjects; those with Hispanic ethnicity, US birthplace, and higher level of household education; and those currently working (all P  ≤ .02, logistic regression). Conclusions This study provides US population–based estimates of eczema prevalence and asthma associations in adults. The results suggest multiple demographic and socioeconomic influences on the US prevalence of adult eczema.

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The Atopic March: Progression from Atopic Dermatitis to Allergic Rhinitis and Asthma.

TL;DR: Recent studies support the idea of a causal link between AD and later onset atopic disorders and suggest that a dysfunctional skin barrier serves as a site for allergic sensitization to antigen and colonization of bacterial super antigens.
References
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Journal ArticleDOI

Controlling the false discovery rate: a practical and powerful approach to multiple testing

TL;DR: In this paper, a different approach to problems of multiple significance testing is presented, which calls for controlling the expected proportion of falsely rejected hypotheses -the false discovery rate, which is equivalent to the FWER when all hypotheses are true but is smaller otherwise.
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The natural course of atopic dermatitis from birth to age 7 years and the association with asthma.

TL;DR: Early wheeze and a specific sensitization pattern were significant predictors for wheezing at school age, irrespective of AD, and the prognosis is mostly determined by the severity and the presence of atopic sensitization.
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Eczema Prevalence in the United States: Data from the 2003 National Survey of Children's Health

TL;DR: Prevalence ranged from 8.7 to 18.1% between states and districts, with the highest prevalence reported in many of the East Coast states, as well as in Nevada, Utah, and Idaho.
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Investigating international time trends in the incidence and prevalence of atopic eczema 1990-2010: a systematic review of epidemiological studies.

TL;DR: A systematic search for high quality reports of cohort, repeated cross-sectional and routine healthcare database-based studies in seven electronic databases found evidence suggesting that the prevalence of atopic eczema was increasing in Africa, eastern Asia, western Europe and parts of northern Europe.
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Update on risk factors for food allergy.

TL;DR: An alternative hypothesis is proposed, suggesting that early cutaneous Exposure to food protein through a disrupted skin barrier leads to allergic sensitization and that early oral exposure to food allergen induces tolerance.
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