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Journal ArticleDOI

Advances in drug delivery and medical imaging using colloidal lyotropic liquid crystalline dispersions.

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TLDR
The overarching goal of this feature article is to review the recent developments in the field of drug delivery specifically involving colloidal lyotropic liquid crystalline dispersions, and the types of therapeutic compounds and medical imaging agents that can be incorporated as well as their methods of preparation.
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This article is published in Journal of Colloid and Interface Science.The article was published on 2013-03-01. It has received 268 citations till now. The article focuses on the topics: Drug delivery.

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Nanomaterials for In Vivo Imaging

TL;DR: This work addresses the physicochemical makeup/design of nanomaterials through the lens of the physical properties that produce contrast signal for the cognate imaging modality-the authors stratify nanommaterials on the basis of their (i) magnetic, (ii) optical, (iii) acoustic, and/or nuclear properties.
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Advances in Structural Design of Lipid-Based Nanoparticle Carriers for Delivery of Macromolecular Drugs, Phytochemicals and Anti-Tumor Agents

TL;DR: It is concluded that the structural design of the nanoparticulate carriers is of crucial importance for the therapeutic outcome and the triggered drug release from biocolloids.
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Carotenoid-loaded nanocarriers: A comprehensive review

TL;DR: This review comprehensively covers recent advances in nanoencapsulation of carotenoids with biopolymeric nanocarriers (polysaccharides and proteins), and lipid-based nanoccarriers, their functionalities, aptness and innovative developments in preparation strategies.
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Lyotropic liquid crystal engineering moving beyond binary compositional space – ordered nanostructured amphiphile self-assembly materials by design

TL;DR: In this critical review, the phase transitions upon encapsulation of more than 130 amphiphilic and soluble additives into the bicontinuous lipidic cubic phase under excess hydration are summarized.
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Non-Lamellar Lyotropic Liquid Crystalline Lipid Nanoparticles for the Next Generation of Nanomedicine

TL;DR: This review provides an overview of the benefits and advantages of using lyotropic liquid crystalline lipid nanoparticles as drug delivery nanocarriers, design principles for making LCNPs with desirable functionalities for drug delivery applications, current understanding of the LLC material-biology interface, and current patenting and translation activities in a pharmaceutical context.
References
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Intermolecular and surface forces

TL;DR: The forces between atoms and molecules are discussed in detail in this article, including the van der Waals forces between surfaces, and the forces between particles and surfaces, as well as their interactions with other forces.
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The fluid mosaic model of the structure of cell membranes.

TL;DR: Results strongly indicate that the bivalent antibodies produce an aggregation of the surface immunoglobulin molecules in the plane of the membrane, which can occur only if the immunoglOBulin molecules are free to diffuse in the membrane.
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Nanocarriers as an emerging platform for cancer therapy

TL;DR: The arsenal of nanocarriers and molecules available for selective tumour targeting, and the challenges in cancer treatment are detailed and emphasized.
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Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review.

TL;DR: The basic characteristics of the EPR effect, particularly the factors involved, are described, as well as its modulation for improving delivery of macromolecular drugs to the tumor.
Journal ArticleDOI

Recent advances with liposomes as pharmaceutical carriers.

TL;DR: For further successful development of this field, promising trends must be identified and exploited, albeit with a clear understanding of the limitations of these approaches.
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