Aggregation of Cartilage Proteoglycans I. THE ROLE OF HYALURONIC ACID
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TLDR
Evidence is presented which suggests that the hyaluronic acid-proteoglycan interactions described by Hardingham and Muir ((1972) Biochim.About:
This article is published in Journal of Biological Chemistry.The article was published on 1974-07-10 and is currently open access. It has received 539 citations till now. The article focuses on the topics: Hyaluronic acid & Proteoglycan.read more
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Proteoglycans in the Developing Brain: New Conceptual Insights for Old Proteins
TL;DR: This review summarizes the most recent data on structures and functions of brain proteoglycans and focuses on new physiological concepts for their potential roles in the developing central nervous system.
Journal ArticleDOI
Properties of dissociatively extracted fetal tooth matrix proteins. I. Principal molecular species in developing bovine enamel.
TL;DR: In fetal bovine enamel, the initial dissociative extraction step completely removes proline-rich amelogenins from the tissue without dissolving the enamel apatite, and gel filtration data showed a clear shift in molecular size population from higher to lower components for both amelgenins and enamelins with progressive enamel maturation.
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Isolation and characterization of proteoglycans from the swarm rat chondrosarcoma.
TL;DR: Proteoglycan monomer (D1) and aggregate (A1) preparations were isolated from 4 M guanidinium chloride extracts of the Swarm rat chondrosarcoma and contained only small proteoglycan fragments, indicating that extensive enzymatic degradation had occurred.
Journal ArticleDOI
Hyaluronan and homeostasis : a balancing act
TL;DR: The results obtained imply that conventional chemotherapy may be a viable treatment for lung cancer in women without a prior history of immunological disease.
References
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Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis
Klaus Weber,Mary Osborn +1 more
TL;DR: The results show that the polyacrylamide gel electrophoresis method can be used with great confidence to determine the molecular weights of polypeptide chains for a wide variety of proteins.
Journal ArticleDOI
A modified uronic acid carbazole reaction
T. Bitter,Helen Muir +1 more
TL;DR: It has been found possible to distinguish betweenHeparin, heparin derivatives, and other polyuronides of connective tissue by comparing the effect of chlorides on the color yield in both procedures by modifying Dische's carbazole reaction for uronic acid in the presence of borate.
Journal ArticleDOI
Purification and Properties of Bacterial Chondroitinases and Chondrosulfatases
TL;DR: An enzyme, "chondroitinase-ABC," has been purified to apparent homogeneity from extracts of Proteus vulgaris, NCTC 4636, which was adapted on a medium containing chondroit in sulfate C, and its properties have been compared with those of chondro-4-sulfatase- ABC from P. vulgaris.
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