Alginate: properties and biomedical applications
Kuen Yong Lee,David J. Mooney +1 more
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TLDR
This review will provide a comprehensive overview of general properties of alginate and its hydrogels, their biomedical applications, and suggest new perspectives for future studies with these polymers.About:
This article is published in Progress in Polymer Science.The article was published on 2012-01-01 and is currently open access. It has received 5372 citations till now. The article focuses on the topics: Self-healing hydrogels.read more
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Nano based drug delivery systems: recent developments and future prospects
Jayanta Kumar Patra,Gitishree Das,Leonardo Fernandes Fraceto,Leonardo Fernandes Fraceto,Estefania Vangelie Ramos Campos,Estefania Vangelie Ramos Campos,Maria del Pilar Rodriguez-Torres,Laura Susana Acosta-Torres,Luis A. Diaz-Torres,Renato Grillo,Mallappa Kumara Swamy,Shivesh Sharma,Solomon Habtemariam,Han-Seung Shin +13 more
TL;DR: An updated summary of recent advances in the field of nanomedicines and nano based drug delivery systems through comprehensive scrutiny of the discovery and application of nanomaterials in improving both the efficacy of novel and old drugs and selective diagnosis through disease marker molecules is presented.
Journal ArticleDOI
Designing hydrogels for controlled drug delivery.
Jianyu Li,David J. Mooney +1 more
TL;DR: This Review discusses how different mechanisms interact and can be integrated to exert fine control in time and space over the drug presentation, and collects experimental release data from the literature and presents quantitative comparisons between different systems to provide guidelines for the rational design of hydrogel delivery systems.
Journal ArticleDOI
Alginate derivatization: a review of chemistry, properties and applications.
Siddhesh N. Pawar,Kevin J. Edgar +1 more
TL;DR: Progress towards controlled synthesis of alginate derivatives, and the properties and applications of these derivatives are reviewed.
Journal ArticleDOI
3D Bioprinting Human Chondrocytes with Nanocellulose-Alginate Bioink for Cartilage Tissue Engineering Applications
Kajsa Markstedt,Athanasios Mantas,Ivan Tournier,Héctor Martínez Ávila,Daniel Hägg,Paul Gatenholm +5 more
TL;DR: A bioink that combines the outstanding shear thinning properties of nanofibrillated cellulose (NFC) with the fast cross-linking ability of alginate with the potential use of nanocellulose for 3D bioprinting of living tissues and organs is formulated.
Journal ArticleDOI
A review on polymeric hydrogel membranes for wound dressing applications: PVA-based hydrogel dressings
TL;DR: In this article, the authors present the past and current efforts with a brief description on the featured properties of hydrogel membranes fabricated from biopolymers and synthetic ones for wound dressing applications.
References
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Polyionic hydrocolloids for the intestinal delivery of protein drugs: alginate and chitosan--a review.
Meera George,T. Emilia Abraham +1 more
TL;DR: Alginate, being an anionic polymer with carboxyl end groups, is a good mucoadhesive agent and cross-linked alginate has more capacity to retain the entrapped drugs and mixing of alginates with other polymers such as neutral gums, chitosan, and eudragit have been found to solve the problem of drug leaching.
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Protein release from alginate matrices.
Wayne R. Gombotz,Siow Fong Wee +1 more
TL;DR: By selection of the type of alginate and coating agent, the pore size, degradation rate, and ultimately release kinetics can be controlled.
Journal ArticleDOI
Alginate hydrogels as biomaterials.
TL;DR: Micro-CT images of bone-like constructs that result from transplantation of osteoblasts on gels that degrade over a time frame of several months leading to improved bone formation are presented.
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BIOMATERIALS: Where We Have Been and Where We Are Going
TL;DR: This new generation of biomaterials includes surface modification of materials to overcome nonspecific protein adsorption in vivo, precision immobilization of signaling groups on surfaces, and design of sophisticated three-dimensional architectures to produce well-defined patterns for diagnostics.
Journal ArticleDOI
Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate
Nathaniel Huebsch,Praveen R. Arany,Praveen R. Arany,Angelo S. Mao,Dmitry Shvartsman,Dmitry Shvartsman,Omar Abdel-Rahman Ali,Sidi A. Bencherif,Sidi A. Bencherif,José Rivera-Feliciano,David J. Mooney,David J. Mooney +11 more
TL;DR: These findings suggest that cells interpret changes in the physical properties of adhesion substrates as changes in adhesion ligand presentation, and that cells themselves can be harnessed as tools to mechanically process materials into structures that feedback to manipulate their fate.
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Alginate hydrogels as synthetic extracellular matrix materials
Hydrogels for tissue engineering: scaffold design variables and applications.
Jeanie L. Drury,David J. Mooney +1 more
Polyionic hydrocolloids for the intestinal delivery of protein drugs: alginate and chitosan--a review.
Meera George,T. Emilia Abraham +1 more