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Journal ArticleDOI

Alkaloids of the Apocynaceae.

Robert F. Raffauf, +1 more
- 01 Jan 1960 - 
- Vol. 14, Iss: 1, pp 37-55
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TLDR
Certain correlations are discernible and may be used by the plant chemist as first approximations of the types of materials he may expect in the analysis of previously unstudied genera.
Abstract
Of the 200 alkaloids in the relatively well-studied Apocynaceae, only 75 have had sufficient chemical investigation to permit their structural identity. Nonetheless, certain correlations are discernible and may be used by the plant chemist as first approximations of the types of materials he may expect in the analysis of previously unstudied genera.

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Citations
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Review on ethnomedicinal, phytochemical and pharmacological evidence of Himalayan anticancer plants.

TL;DR: Certain Himalayan medicinal plants present therapeutic properties against different types of cancer, however, not all of the plants have been fully analysed for in vitro, in vivo and toxicological activities, and isolation of secondary metabolites.
Journal ArticleDOI

Defense sequestration associated with narrowing of diet and ontogenetic change to aposematic colours in the spotted lanternfly

TL;DR: The results highlight the importance of the pan-tropical taxon Fulgoridae for evolutionary biology of complex aposematic strategies and for understanding the links between timing of defense sequestration, timing of host plant preference shifts, and timing of colour change.
Journal ArticleDOI

Apocynaceae species with antiproliferative and/or antiplasmodial properties: a review of ten genera

TL;DR: Apocynaceae is a large family of tropical trees, shrubs and vines with most species producing white latex, which is known for a wide range of biological and pharmacological activities such as cardioprotective, hepatoprotsective, neuroprotective, anti-inflammatory, anticancer and antimalarial properties.
Journal ArticleDOI

Steroid Alkaloids from Holarrhena africana with Strong Activity against Trypanosoma brucei rhodesiense

TL;DR: The extracts and their alkaloid-enriched fractions displayed promising in vitro activity against bloodstream forms of T. brucei rhodesiense and provided useful empirical data for further development of steroid alkaloids as a novel class of anti-trypanosomal compounds.
References
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Journal ArticleDOI

Role of chance observations in chemotherapy: vinca rosea†

TL;DR: The role of chance in obtaining new leads for chemotherapy and the effects of extracts of the plant given orally to experimental animals proved disappointing, and essentially no alterations in the blood sugar of normal or diabetic rats or rabbits could be induced.