Aloe barbadensis Miller peptide/polypeptide fraction alleviates inflammation through inhibition of proinflammatory cytokines and mediators in vitro and in rats with Freund’s adjuvant-induced hind paw edema
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Cites background from "Aloe barbadensis Miller peptide/pol..."
...The flower grows around 90 cm, often being pendulous and consists of yellow tubular corolla around 2–3 cm (Babu et al., 2019)....
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...Apart from that, polyphenols from Aloe species have been reported to possess anti-diabetic potential, anti-inflammatory properties, and wound healing properties (Babu et al., 2019)....
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References
74 citations
"Aloe barbadensis Miller peptide/pol..." refers background in this paper
...The high levels of these proinflammatory mediators and cytokines have been implicated in autoimmune disorders[34]....
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68 citations
"Aloe barbadensis Miller peptide/pol..." refers background in this paper
...The levels of sPLA2 are high in the joints of patients affected with the inflammatory disorder[40,41]....
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67 citations
"Aloe barbadensis Miller peptide/pol..." refers methods in this paper
...Albumin denaturation inhibition assay Different concentrations of PPF (50, 100, 150, 200 and 250 μg/mL) were mixed with 1% bull serum albumin and phosphate-buffered saline and the assay was carried out according to Osman et al[17] with aspirin as standard drug....
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...Protein denaturation inhibition assay and membrane stabilization assay are used to determine the anti-inflammatory property of the extracts[17,18]....
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63 citations
"Aloe barbadensis Miller peptide/pol..." refers methods in this paper
...The plasma was used for the estimation of AST and ALT[26], TNF-α, IL-6, and sPLA2[27] levels through respective ELISA kits as per the manufacturer’s protocol....
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63 citations
"Aloe barbadensis Miller peptide/pol..." refers background in this paper
...MAPK plays a role in the regulation of LPS stimulated NF-κB pathway[42,43]....
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