Journal ArticleDOI
Aloe vera and its two bioactive constituents in alleviation of diabetes -proteomic & mechanistic insights.
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TLDR
In this article, the mechanism of action of Aloe vera and its two constituents (Carbohydrates and Polypeptides) in the alleviation of diabetes in streptozotocin-induced diabetic rats through a proteomics approach was investigated.About:
This article is published in Journal of Ethnopharmacology.The article was published on 2021-11-15. It has received 7 citations till now. The article focuses on the topics: Aloe vera & Zonulin.read more
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Journal ArticleDOI
Aloe vera carbohydrates regulate glucose metabolism through improved glycogen synthesis and downregulation of hepatic gluconeogenesis in diabetic rats.
Swaminathan Govindarajan,Spoorthy N. Babu,Mookambeshwaran A. Vijayalakshmi,Poonkodi Manohar,Ayesha Noor +4 more
TL;DR: In this paper, the antidiabetic effect of Aloe vera carbohydrate fraction (AVCF) was evaluated using α-amylase, α-glucosidase inhibition, glucose diffusion and glucose uptake assay.
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Genus Aloe as sources of antidiabetic, antihyperglycemic and hypoglycemic agents: A review
Mutiu Idowu Kazeem,H. A. Bankole,Azeez A. Fatai,Gbemisola Morounke Saibu,Adedoja Dorcas Wusu +4 more
TL;DR: In this paper , the authors integrated available information on all Aloe spp. with antidiabetic potentials and found that the most common species of Aloe sp. is A. vera and few studies were carried out in vitro while most were performed in vivo.
Journal ArticleDOI
Práticas terapêuticas com plantas medicinais para o tratamento do Diabetes Mellitus
Bárbara Mendes Guimarães,Karla Antunes Ramos,Marcio Coutinho de Souza,Mauro Lúcio Franco,Caio César de Souza Alves,Alessandra de Paula Carli,Jandesson Mendes Coqueiro +6 more
TL;DR: Pode-se concluir that os sujeitos adoecidos com Diabetes Mellitus contam com uma variedade of práticas terapêuticas com plantas medicinais para o tratamento, mas seus efeitos devem ser melhor estudados em seres humanos, de forma a assegurar o uso dessas plantas.
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Aloe vera in diabetic dyslipidemia: Improving blood glucose and lipoprotein levels in pre-clinical and clinical studies
Neha Deora,K. Venkatraman +1 more
TL;DR: In this paper , the potential effect of Aloe vera and its active components in alleviating diabetic dyslipidemia, as well as their mechanism of action in pre-clinical and clinical studies is discussed.
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Therapeutic Effect of Aloe vera on Croton Oil Induced Hemorrhoids
TL;DR: In this article , the authors evaluated the efficacy of gel obtained from Aloe barbadensis Miller in treating hemorrhoids in a croton oil-induced Wistar rat model and found that aloe gel is much more effective when compared to Pilex ointment which was used as standard (p<0.05).
References
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Journal ArticleDOI
The Human Plasma Proteome History, Character, and Diagnostic Prospects
TL;DR: This work speculates on the reasons behind this large discrepancy between the expectations arising from proteomics and the realities of clinical diagnostics and suggests approaches by which protein-disease associations may be more effectively translated into diagnostic tools in the future.
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Oxidative stress and diabetic complications
TL;DR: Athrosclerosis and cardiomyopathy in type 2 diabetes are caused in part by pathway-selective insulin resistance, which increases mitochondrial ROS production from free fatty acids and by inactivation of antiatherosclerosis enzymes by ROS.
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Composition and Applications of Aloe vera Leaf Gel
TL;DR: The aim of this review is to further highlight recently discovered effects and applications of the leaf gel of A. vera to enhance the intestinal absorption and bioavailability of co-administered compounds as well as enhancement of skin permeation.
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An evaluation of the biological and toxicological properties of Aloe barbadensis (miller), Aloe vera.
Boudreau,Frederick A. Beland +1 more
TL;DR: A review of the botany, physical and chemical properties, and biological activities of the Aloe vera plant finds that it contains multiple constituents with potential biological and toxicological activities, yet the active components elude definition.
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The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus.
Philipp A. Gerber,Guy A. Rutter +1 more
TL;DR: Better understanding of the role of oxidative changes, its modulation by genes involved in disease risk, and effects on beta-cell identity may facilitate the development of new therapeutic strategies to this disease.