Alterations in sperm characteristics of follicle-stimulating hormone (FSH)-immunized men are similar to those of FSH-deprived infertile male bonnet monkeys.
Citations
325 citations
294 citations
Cites background from "Alterations in sperm characteristic..."
...…ApafI apoptotic protease-activating factor I (Apaf-1) spermatogonial degeneration Honarpour et al. (2000) Fshr FSH receptor decreased testis size Krishnamurthy et al. (2000) Sycp3 synaptonemal complex protein 3 germ cell apoptosis during meiotic prophase Yuan et al. (2000) Bcl-6 Bcl-6 protein…...
[...]
182 citations
94 citations
Cites background from "Alterations in sperm characteristic..."
...The regulation of spermiogenesis covering the post-meiotic development of male germ cells has been linked to androgen levels (McLachlan et al., 2002) and to FSH levels (Krishnamurthy et al., 2000) whereas spermiation seems to be dependent on both testosterone and FSH levels....
[...]
83 citations
Cites background from "Alterations in sperm characteristic..."
...It is interesting to note that the elongated spermatids of the adult FORKO male [15] as well as FSH-immunized monkeys [45] exhibit improper nuclear compaction....
[...]
References
34 citations
"Alterations in sperm characteristic..." refers background in this paper
...…are leading toward a clear consensus on the need for FSH in maintaining normal spermatogenesis in monkeys (Murty et al, 1979; Wickings et al, 1980; Moudgal, 1981; Raj et al, 1982; Van Alpen et al, 1988; Weinbauer et al, 1991; Moudgal et al, 1992) and in men (Matsumoto et al, 1986; Gromoll et al,…...
[...]
25 citations
"Alterations in sperm characteristic..." refers background or methods or result in this paper
...This is clearly suggestive of defective spermiogenesis (Aravindan et al, 1997)....
[...]
...Further, we also have observed that FSH deprivation in monkeys affects sperm chromatin status as determined by the ability of sperm to undergo nuclear decondensation following exposure to a reducing agent like dithiothreitol (DTT; Aravindan et al, 1997, and unpublished data)....
[...]
...The procedure for obtaining sperm nuclear decondensation by exposure to various concentrations of DTT has been described earlier (Aravindan et al, 1995, 1997)....
[...]
...These results concur with our earlier observations of increased susceptibility to DTT-induced decondensation of ejaculated and epididymal sperm from oFSH immunized monkeys (Aravindan et al, 1997)....
[...]
22 citations
"Alterations in sperm characteristic..." refers background in this paper
...There is a large body of evidence in favor and against FSH’s role in regulating spermatogenesis (Dym et al, 1979; Vaishnav and Moudgal, 1994; Sinha Hikkim and Swerdloff, 1995; Shetty et al, 1996)....
[...]
15 citations
"Alterations in sperm characteristic..." refers background in this paper
...Loss of FSH action in sheep leads to decreases in daily production of B2 spermatogonia, leptotene, and 317Krishnamurthy et al · FSH Deprivation Affects Sperm Quality pachytene spermatocytes (Kilgour et al, 1993)....
[...]
...In other species, such as hamsters (Lerchl et al, 1993) and sheep (Kilgour et al, 1993), completion of spermatogenesis is dependent on FSH stimulation of testicular function....
[...]
6 citations
"Alterations in sperm characteristic..." refers methods in this paper
...The procedure for obtaining sperm nuclear decondensation by exposure to various concentrations of DTT has been described earlier (Aravindan et al, 1995, 1997)....
[...]