American Gastroenterological Association Institute Technical Review on the Role of Elastography in Chronic Liver Diseases.
TL;DR: This technical review addresses focused questions related to comparative diagnostic performance of VCTE and MRE relative to nonproprietary, serum-based fibrosis markers for detection of cirrhosis in patients with hepatitis C virus, hepatitis B virus, NAFLD, and alcoholic liver diseases.
About: This article is published in Gastroenterology.The article was published on 2017-05-01 and is currently open access. It has received 205 citations till now. The article focuses on the topics: Transient elastography & Chronic liver disease.
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TL;DR: This AASLD 2018 Hepatitis B Guidance provides a data-supported approach to screening, prevention, diagnosis, and clinical management of patients with hepatitis B.
2,399 citations
Cites background from "American Gastroenterological Associ..."
...aspartate aminotransferase [AST] to platelet ratio index or FIB-4) in predicting significant or advanced fibrosis.((123,124)) Noninvasive methods overestimate fibrosis if high levels of necroinflammation, as reflected by elevated ALT, are present....
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TL;DR: The latest data on the treatment and management of alcohol-related liver disease will be reviewed and up to date recommendations for clinical management will be provided.
476 citations
TL;DR: In an analysis of data from a large prospective study of patients with hepatitis C virus-associated compensated or decompensated cirrhosis, it is found that the SVR to DAA treatment decreased the incidence of HCC over a mean follow-up of 14 months.
276 citations
TL;DR: A pooled analysis of data from individual participants with biopsy‐proven NAFLD found MRE to have a statistically significantly higher diagnostic accuracy than TE in detection of each stage of fibrosis.
236 citations
TL;DR: The Expanded‐Baveno VI criteria performed well in patients with cACLD with hepatitis C virus and alcoholic and nonalcoholic steatohepatitis and would potentially spare more endoscopies than the original criteria with a minimal risk of missing VNT in most of the main etiologies of cAC LD.
208 citations
Cites background from "American Gastroenterological Associ..."
...This threshold was decided by experts in the Baveno VI consensus conference who agreed that 5% was a reasonable threshold for missing VNT; it was later endorsed by the American Gastroenterological Association technical review on hepatic elastography accepting a 5% false negative rate of missing high risk varices.((4,12,18)) The choice of new cut-off values for the different parameters explored was based on published reports....
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References
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TL;DR: A substantial proportion of the worldwide burden of cancer could be prevented through the application of existing cancer control knowledge and by implementing programs for tobacco control, vaccination, and early detection and treatment, as well as public health campaigns promoting physical activity and a healthier dietary intake.
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