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Journal ArticleDOI

Amides from Piper brachystachyum and Piper retrofractum.

01 Apr 2002-Phytochemistry (Pergamon)-Vol. 59, Iss: 8, pp 897-901
TL;DR: Three unsaturated amides, designatedBrachystamides-C, D and E have been characterised from Piper brachystachyum Wall, which yielded retrofractamide-D, which has been fully characterised.
About: This article is published in Phytochemistry.The article was published on 2002-04-01. It has received 22 citations till now. The article focuses on the topics: Piper retrofractum.
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Book ChapterDOI
01 Jan 2004
TL;DR: The phytochemistry of the genus Piper is rich in terms of numbers of compounds discovered, but given the diversity of this genus and the intraspecific diversity of secondary metabolites in those species that have been examined, Piper chemistry has not been adequately investigated.
Abstract: The phytochemistry of the genus Piper is rich in terms of numbers of compounds discovered, but given the diversity of this genus and the intraspecific diversity of secondary metabolites in those species that have been examined, Piper chemistry has not been adequately investigated. The natural products chemistry that has been elucidated is well documented and has been the subject of extensive review (Sengupta and Ray 1987, Parmar et al. 1997). Since those reviews were published, 28 new species have been investigated (Benevides et al. 1999, Chen et al. 2002, Ciccio 1997, de Abreu et al. 2002, Dodson et al. 2000, dos Santos et al. 2001, Facundo and Morais 2003, Jacobs et al. 1999, Joshi et al. 2001, Martins et al. 1998, Masuoka et al. 2002, McFerren and Rodriquez 1998, Moreira et al. 1998, Mundina et al. 1998, Srivastava et al. 2000a, Stohr et al. 2001, Terreaux et al. 1998, Torquilho et al. 2000, Vila et al. 2001, 2003, Wu et al. 1997), and 69 compounds new to Piper have been discovered (Adesina et al. 2002, Alecio et al. 1998, Baldoqui et al. 1999, Banerji et al. 1993, 2002b, Boll et al. 1994, Chen et al. 2002, Ciccio 1997, Da Cunha and Chaves 2001, Das and Kashinatham 1998, daSilva et al. 2002, de Araujo-Junior et al. 1997, Dodson et al. 2000, Gupta et al. 1999, Jacobs et al. 1999, Joshi et al. 2001, Martins et al. 1998, Masuoka et al. 2002, Menon et al. 2000, 2002, Moreira et al. 1998, 2000, Mundina et al. 1998, Navickiene et al. 2000, Pande et al. 1997, Parmar et al. 1998, Santos and Chaves 1999a,b, Santos et al. 1998, Seeram et al. 1996, Siddiqui et al. 2002, Srivastava et al. 2000a,b, Stohr et al. 1999, Terreaux et al. 1998, Wu et al. 2002a,b, Zeng et al. 1997).

64 citations


Cites background from "Amides from Piper brachystachyum an..."

  • ...…al. 2001, 2003, Wu et al. 1997), and 69 compounds new to Piper have been discovered (Adesina et al. 2002, Alecio et al. 1998, Baldoqui et al. 1999, Banerji et al. 1993, 2002b, Boll et al. 1994, Chen et al. 2002, Ciccio 1997, Da Cunha and Chaves 2001, Das and Kashinatham 1998, daSilva et al. 2002,…...

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  • ...…al. (1980), Miyakado et al. (1989), Strunz and Finlay (1994), Kiuchi et al. (1997), Das and Madhusudhan (1998), de Mattos Duarte et al. (1999), de Araújo-Júnior et al. (1999, 2001), EVOLUTIONARY ECOLOGY OF Piper AMIDES 127 de Paula et al. (2000), Scott et al. (2002), and Banerji et al. (2002a)....

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Journal ArticleDOI
TL;DR: Detailed chemical studies on the roots of Piper sarmentosum and Piper nigrum have resulted in several alkaloids, including a new aromatic compound, 1-nitrosoimino-2,4,5-trimethoxybenzene (1).

51 citations


Cites background from "Amides from Piper brachystachyum an..."

  • ...…(3) (Schobert et al., 2001), 2,4-tetradecadienoic acid isobutyl amide (4) (Greger et al., 1981), piperine (5) (Parmar et al., 1998), sylvamide (6) (Banerjit et al., 2002), cepharadione A (7) (Akasu et al., 1990), piperolactam D (8) (Sanjay et al., 1974) and paprazine (9) (Ikuo et al., 1991)....

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  • ..., 1998), sylvamide (6) (Banerjit et al., 2002), cepharadione A (7) (Akasu et al....

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Journal ArticleDOI
07 May 2013-Analyst
TL;DR: The results demonstrate that this 2D NPLC × RPLC method with good orthogonality was effective for the preparative separation and purification of amide alkaloids from Piper longum L.
Abstract: A comprehensive off-line two-dimensional liquid chromatography (2D-LC) method coupling normal phase liquid chromatography (NPLC) and reversed phase liquid chromatography (RPLC) was developed for separation and purification of amide alkaloids from Piper longum L. In the first dimension, the crude alkaloid fractions were separated in NPLC mode and 20 fractions were collected. Then fractions 5-20 were selected for further purification in RPLC mode in the second dimension. The purities of RPLC fractions with similar structures were all identified accurately by ultra performance liquid chromatography (UPLC). In total, 28 compounds with high purity were obtained and their structures were comprehensively characterized by electrospray ionization-mass spectrometry (ESI-MS) and nuclear magnetic resonance (NMR) spectroscopy. The results demonstrate that this 2D NPLC × RPLC method with good orthogonality (58.3%) was effective for the preparative separation and purification of amide alkaloids from Piper longum L.

50 citations

Journal ArticleDOI
TL;DR: In this review, the various aspects of secondary metabolites, production synthesis, and sources of medical products from plant sources are discussed.
Abstract: Plants are the source of various photochemicals; metabolites are used in medicinal and environmental sectors as well as being widely used in commercial and pharmaceutical products. Although they produce a number of medicinal products, either already on the market or under trial, the amounts obtained from plant sources are very minute or difficult to synthesize at an industrial level due to the complex chemical composition and chirality exhibited by these compounds. However, plant cell cultures offer a good alternative for the consistent production of desired secondary metabolites under the influence of precursors and elicitors. In this review, we discuss the various aspects of secondary metabolites, production synthesis, and sources of medical products from plant sources.

50 citations

References
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Journal ArticleDOI
TL;DR: In this article, two unsaturated amides, retrofractamides A and C, were isolated from the total aboveground parts of Piper retroractum and were shown to be N -isobutyl-9(3′,4′-methylenedioxyphenyl)2 E,4 E,8 E -nonatrienamide from spectroscopic and chemical investigations.

42 citations

Journal ArticleDOI
TL;DR: Two new unsaturated amides were isolated from the total above-ground parts of Piper brachystachyum and were shown to be N-isobutyl-15 (3′,4′-methylenedioxyphenyl) 2E,4E-pentadecadienamide from spectroscopic and chemical investigations.

25 citations

Journal ArticleDOI
TL;DR: Extraction of the stems and leaves of Piper ridleyi with ether afforded N - iso butyl-15-(3′,4′-methylenedioxyphenyl)-2 E,4 E,12 E -pentadecatrienamide (ridleyamide), as well as the known amide, retrofractamide, and sterols was described in this paper.

18 citations

Journal ArticleDOI
TL;DR: In this article, the authors complete the composition and composes apparentes d'apres les schemas de decomposition des spectres couples, de l'application des relations d'additivite and des comparaisons internes des deplacements chimiques.
Abstract: Attribution complete du spectre de ce compose et de composes apparentes d'apres les schemas de decomposition des spectres couples, de l'application des relations d'additivite et des comparaisons internes des deplacements chimiques

5 citations