Proceedings ArticleDOI
An Efficient Single-Fault Detection Technique for Micro-fluidic Based Biochips
Sagarika Saha,Amlan Chakraborti,Samir Roy +2 more
- pp 10-14
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TLDR
A new technique is presented to traverse all the cells and cell boundary, for the purpose of detecting a single fault within the bio-chip, and results show that the proposed technique improves the fault detection time to a great extent.Abstract:
This paper presents a new fault detection technique for digital micro-fluidic based biochips. Due to recent advances in microfluidics, digital micro-fluidic biochips are revolutionizing laboratory procedures, e.g., biosensing, clinical diagnostics etc. Because of the underlying mixed-technology and mixed energy domains, biochips exhibit unique failure mechanisms and defects. Off-line and on-line test techniques are required to ensure system dependability. In this paper, a new technique is presented to traverse all the cells and cell boundary, for the purpose of detecting a single fault within the bio-chip. Experimental results show that the proposed technique improves the fault detection time to a great extent.read more
Citations
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Journal ArticleDOI
Reactant and Waste Minimization in Multitarget Sample Preparation on Digital Microfluidic Biochips
TL;DR: A multitarget sample preparation algorithm that extensively exploits the ideas of waste recycling and intermediate droplet sharing to reduce both reactant usage and waste amount for digital microfluidic biochips is proposed.
Proceedings ArticleDOI
An efficient novel single fault and its location detection technique using multiple droplets in a Digital Microfluidic Biochip
TL;DR: The proposed technique for detecting a single fault and identifying the fault location within the biochip can also calculate the traversal time if the bio chip is fault free and represents significant improvement in fault detection and calculating traverse time of a fault free biochip over existing methods.
Book ChapterDOI
A Multi Droplets Detection Technique for Single-Fault in Digital Micro-fluidic Biochip
TL;DR: The key idea is to manipulate multiple droplets in parallel to test the micro-array in a scan-like manner and show significant improvement in fault detection over existing methods.
Journal ArticleDOI
A particle swarm optimization method for fault localization and residue removal in digital microfluidic biochips
TL;DR: A novel test droplet routing method based on adaptive weighted particle swarm optimization (PSO) model aims to identify defective electrodes and simultaneously performs residue removal and reveals operational supremacy in terms of overall computational time and operational accuracy over some existing best known models.
Proceedings ArticleDOI
Iterative Parallel Test to Detect and Diagnose Multiple Defects for Digital Microfluidic Biochip
TL;DR: This work is presenting an efficient parallel testing and diagnosis scheme to reveal the location of all the faulty electrodes in digital microfluidic biochip, and is capable to check the given biochip with other concurrently running bioassay operations.
References
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An integrated digital microfluidic lab-on-a-chip for clinical diagnostics on human physiological fluids
TL;DR: This work presents an alternative paradigm--a fully integrated and reconfigurable droplet-based "digital" microfluidic lab-on-a-chip for clinical diagnostics on human physiological fluids, and demonstrates reliable and repeatable high-speed transport of microdroplets.
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TL;DR: In this paper, an alternative approach to microfluidics based upon the micromanipulation of discrete droplets of aqueous electrolyte by electrowetting is reported.
Proceedings ArticleDOI
A digital microfluidic biosensor for multianalyte detection
TL;DR: A microfluidic lab-on-chip (LoC) for measuring the concentration of human body metabolites, using submicroliter droplets as reaction chambers, is presented in this article.
Proceedings ArticleDOI
Architectural-level synthesis of digital microfluidics-based biochips
Fei Su,Krishnendu Chakrabarty +1 more
TL;DR: A system design methodology is proposed that attempts to apply classical architectural-level synthesis techniques to the design of digital microfluidics-based biochips and develops an optimal scheduling strategy based on integer linear programming and two heuristic techniques that scale well for large problem instances.
Journal ArticleDOI
BioRoute: A Network-Flow-Based Routing Algorithm for the Synthesis of Digital Microfluidic Biochips
TL;DR: The first network-flow-based routing algorithm that can concurrently route a set of noninterfering nets for the droplet routing problem on biochips is presented and is presented as the first polynomial-time algorithm for simultaneous routing and scheduling using the global-routing paths with a negotiation- based routing scheme.