An efficient synthesis of 5-benzoyloxazolines by regio- and stereo-controlled reaction of N-substituted 2-benzoylaziridines under microwave irradiation
TL;DR: In this paper, Nal was used as an efficient catalyst under microwave irradiation in short reaction times (5-10 mins) and the structure of the regioisomeric product was confirmed by X-ray analysis.
About: This article is published in Journal of Heterocyclic Chemistry.The article was published on 2008-11-01. It has received 33 citations till now.
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TL;DR: This rapid method produced the products in short reaction times (4-5min) and excellent yields (88-97%).
65 citations
TL;DR: A convenient one-pot protocol was developed for the synthesis of 2-imino-1,3-thiazolidin-4-ones by the reaction of amines, isocyanates, aldehydes, and chloroform in the presence of sodium hydroxide under ultrasonic conditions in high yields and shorter reaction times.
60 citations
TL;DR: A facile and convenient protocol was developed for the fast and high yielding synthesis of fused 1,4-dihydropyridines from dimedone in the presence of HY-zeolite as an efficient recyclable heterogeneous catalyst.
Abstract: A facile and convenient protocol was developed for the fast (2.5-3.5 h) and high yielding (70-90 %) synthesis of fused 1,4-dihydropyridines from dimedone in the presence of HY-zeolite as an efficient recyclable heterogeneous catalyst.
59 citations
Cites background from "An efficient synthesis of 5-benzoyl..."
...Recent developments in 1,4-dihydropyridine chemistry and our continued interest in the development of efficient and environmentally friendly procedures for the synthesis of heterocyclic compounds [16-23], prompted us to study the conversion of dimedone into fused 1,4-dihydropyridines in the presence of HY zeolite (Si/Al: 2....
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TL;DR: Novel fused 1H-benzo[f]chromen-indole derivatives were synthesized regioselectivly in good to high yields by triethyl amine catalyzed condensation of 3-cyanoacetylindoles, β-naphthol and aryl aldehydes in methanol under ultrasounic irradiations and conventional conditions.
48 citations
TL;DR: A convenient protocol was developed for the synthesis of the Baylis-Hillman adducts in the presence of weak Lewis base and l-proline at room temperature under ultrasound irradiation and provided the products in good to high yields and reasonable reaction times.
37 citations
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TL;DR: In this article, the effect of substituents on ring openings, rearrangements and use as chiral ligands and auxiliaries is discussed, with a focus on substituent substitutions.
Abstract: Due to their ready availability in chiral form, and propen- sity to undergo regio- and stereoselective ring opening, aziridines have found widespread use in asymmetric synthesis. This review at- tempts to summarise the breadth of use of chiral aziridines in syn- thesis that has recently been reported. Particular emphasis is put on the effect of substituents on ring openings, rearrangements and use as chiral ligands and auxiliaries.
500 citations
TL;DR: The use of chiral oxazolines as ligands in asymmetric catalysis has been extensively studied in the literature as mentioned in this paper, with a large number of important publications detailing oxazoline-related chemistry, suggesting that research in this area, as in synthetic organic chemistry in general, has yet to mature.
492 citations
335 citations