An estimate of the total number of true human miRNAs.
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...Considering that several thousands of miRNAs have already been discovered, many novel miRNA candidates have been additionally proposed (7), while the total number of human miRNAs is estimated to be 2300 (8)....
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...Since the number of miRNAs discovered is steadily rising (7), a remarkable amount of studies already validated microRNA target genes and their function in a multitude of cell-types, tissues and disease phenotypes (8,9)....
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"An estimate of the total number of ..." refers methods in this paper
...We chose HEK 293T cell culture as expression system that stems from a kidney of a healthy aborted fetus and that allows high transfection efficiency and high expression rates for the pSG5 vector (36,37)....
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"An estimate of the total number of ..." refers background in this paper
...In 2014, miRBase defined criteria for high-confidence miRNAs, which represented only 16% of the human miRNAs annotated in release 21 (19)....
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