Journal ArticleDOI
Analgesic and anti-inflammatory properties of brucine and brucine N-oxide extracted from seeds of Strychnos nux-vomica.
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TLDR
The results suggest that central and peripheral mechanism are involved in the pain modulation and anti-inflammation effects of brucine and Brucine N-oxide, biochemical mechanisms of bru cine and brucines N -oxide are different even though they are similar in chemical structure.About:
This article is published in Journal of Ethnopharmacology.The article was published on 2003-10-01. It has received 182 citations till now. The article focuses on the topics: Brucine & Strychnos nux-vomica.read more
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Journal ArticleDOI
Recent developments in anti-inflammatory natural products.
Raju Gautam,Sanjay M. Jachak +1 more
TL;DR: The present review article describes anti‐inflammatory natural products derived from plants and marine sources reported during last decade, which belong to different chemical classes such as alkaloids, steroids, terpenoids, polyphenolics, phenylpropanoids, fatty acids and lipids, and various miscellaneous compounds.
Journal ArticleDOI
Identification of Novel Anti-inflammatory Agents from Ayurvedic Medicine for Prevention of Chronic Diseases: “Reverse Pharmacology” and “Bedside to Bench” Approach
Bharat B. Aggarwal,Sahdeo Prasad,Simone Reuter,Ramaswamy Kannappan,Vivek R. Yadav,Byoungduck Park,Ji Hye Kim,Subash C. Gupta,Kanokkarn Phromnoi,Chitra Sundaram,Seema Prasad,Madan M. Chaturvedi,Bokyung Sung +12 more
TL;DR: Ayurveda, a science of long life, almost 6,000 years old, can serve as a "goldmine" for novel anti-inflammatory agents used for centuries to treat chronic diseases, and description of various Ayurvedic plants currently used for treatment, their active chemical components, and the inflammatory pathways that they inhibit are provided.
Journal ArticleDOI
Role of plant alkaloids on human health: A review of biological activities
Bikash Debnath,Waikhom Somraj Singh,Manik Das,Sanchari Goswami,Mahesh Kumar Singh,Debasish Maiti,Kuntal Manna +6 more
TL;DR: This review has focused on marketed and experimental alkaloids and summarized sources and biological activities of reported alkaloid in past decades.
Book
Medicinal Plants of Asia and the Pacific
TL;DR: This chapter discusses medicinal Plants in the Family Annonaceae, focusing on the phytochemical properties of Fissistima lanuginosum, which is a synthesis of the fruit of fissistigma manubriatum and phytochemistry.
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Anti-inflammatory activity of alkaloids: an update from 2000 to 2010.
Augusto Lopes Souto,Josean Fechine Tavares,Marcelo Sobral da Silva,Margareth de Fátima Formiga Melo Diniz,Petrônio Filgueiras de Athayde-Filho,José Maria Barbosa Filho +5 more
TL;DR: The aim of this review is to review naturally sourced alkaloids with anti-inflammatory effects reported from 2000 to 2010, and the most studied type were the isoquinolines.
References
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Journal ArticleDOI
Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs
TL;DR: The potency ratios obtained for aspirin, phenylbutazone and hydrocortisone are fairly close to the ratios of their respective daily doses in the treatment of rheumatic disease.
Journal Article
The formalin test: an evaluation of the method.
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The formalin test: an evaluation of the method.
TL;DR: The main features of the formalin test are described, including the characteristics of the stimulus and how changes in nociceptive behaviour may be measured and interpreted, and it is argued that the peripheral tissue temperature as well as other factors influencing the peripheral inflammation may affect the response.
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Modified formalin test: characteristic biphasic pain response.
TL;DR: The results indicate that the first and second phase responses induced by formalin have distinct characteristic properties, and it is a very useful method for examining pain, nociception and its modulation by pharmacological or other means.
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Nitric oxide : a key mediator in the early and late phase of carrageenan-induced rat paw inflammation
Daniela Salvemini,Zhi-Qiang Wang,Pamela S. Wyatt,David M. Bourdon,Margaret H. Marino,Pamela T. Manning,Mark G. Currie +6 more
TL;DR: The results suggest that the NO produced by cNOS is involved in the development of inflammation at early time points following carrageenan administration and that No2−/NO3− or PGE2 production in the paw exudate is involvedin the maintenance of the inflammatory response at later time points.