Journal ArticleDOI
Analysis of a functional change in membrane in the process of cell transformation by Rous sarcoma virus; alteration in the characteristics of sugar transport.
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TLDR
Significant alteration in the kinetics of sugar transport occurs in the infected cells concomitant with changes in cell morphology and these alterations appear to be expressed by the transforming gene(s) of RSV and are not found in cells infected with an avian leukosis virus.About:
This article is published in Virology.The article was published on 1970-08-01. It has received 220 citations till now. The article focuses on the topics: Rous sarcoma virus & Virus.read more
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Acidic extracellular microenvironment and cancer
Yasumasa Kato,Shigeyuki Ozawa,Chihiro Miyamoto,Yojiro Maehata,Atsuko Suzuki,Toyonobu Maeda,Yuh Baba +6 more
TL;DR: CO2 from the pentose phosphate pathway is an alternative source of acidity, showing that hypoxia and extracellular acidity are, while being independent from each other, deeply associated with the cellular microenvironment.
Journal ArticleDOI
Changes in surface morphology of chinese hamster ovary cells during the cell cycle
TL;DR: Synchronized populations of Chinese hamster ovary (CHO) cells in confluent culture have been examined by scanning electron microscopy and their surface changes noted as the cells progress through the cycle reflect the changing capacity of CHO cells during the cycle to respond to contact with other cells in the population.
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The effects of reciprocal changes in temperature on the transformed state of cells infected with a rous sarcoma virus mutant.
TL;DR: The results strongly suggest that a virus-coded, heat-labile protein, which is not a structural component of the virus, plays an essential role in cell transformation by the mutant.
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Transport of nucleosides, nucleic acid bases, choline and glucose by animal cells in culture.
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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On the cooperativity of biological membranes.
TL;DR: The Monod-Wyman-Changeux of allosteric transitions in enzyme-substrate reactions to a membrane composed of identical units (protomers) is extended and it appears possible to have a first-order phase transition when the chemical potential of the substrate is varied, holding the temperature constant.
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Studies of tissue permeability. V. The penetration and phosphorylation of 2-deoxyglucose in the rat diaphragm.
David M. Kipnis,Carl F. Cori +1 more
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Rapid transformation of cells by rous sarcoma virus
TL;DR: Two factors, the treatment of cells with DEAE-dextran and the use of cells which grow rapidly following virus infection, are found to be most important for synchronous transformation of chick embryo cells by infection with Rous sarcoma virus.
Journal ArticleDOI
Enzymatic Microdetermination of Glucose in Blood and Urine
L. L. Salomon,J. E. Johnson +1 more