Anatomical Variation in the Amount and Composition of Human Skin Surface Lipid
TL;DR: The results indicate that lipid produced by the epidermis is an insignificant fraction of the total extractable surface lipid on areas rich in sebaceous glands, but can affect surface lipid composition on the limbs and on the trunk away from the midline.
About: This article is published in Journal of Investigative Dermatology.The article was published on 1970-03-01 and is currently open access. It has received 277 citations till now. The article focuses on the topics: Human skin.
Citations
More filters
Book•
01 Nov 1991TL;DR: In this article, a concise history of fingerprinting and a discussion of Live-Scan and Image Transmission networks are discussed, including physical, chemical, instrumental, and combination techniques, as well as new developments in fingerprint processing.
Abstract: Major new developments in fingerprint processing are covered in this text - including physical, chemical, instrumental and combination techniques. Also included are a concise history of fingerprinting and a discussion of Live-Scan and Image Transmission networks.
482 citations
TL;DR: The axillary microflora of 229 subjects was characterized quantitatively and the results correlated with whether the odor was pungent body odor or instead a faint "acid odor", found to be a stable mixture of Micrococcaceae, aerobic diphtheroids and Propionibacteria.
361 citations
TL;DR: The knowledge of the histopathology, lipid abnormalities and role of microorganisms in meibomian gland dysfunction is outlined and effective treatments available are discussed.
330 citations
TL;DR: There is a real need to conduct future research on the composition of fingermark residue, focusing particularly on quantitative measurements, aging kinetics and effects of influence factors, for advances in fingermark enhancement and dating technique developments.
283 citations
Cites background from "Anatomical Variation in the Amount ..."
...Numerous publications have studied the compounds secreted by the eccrine and sebaceous glands for dermatological or medical purposes [1–6,68,79–84], but only a few focused on the ones generated by these glands and identified in fingermark residue....
[...]
TL;DR: The tape stripping method in its standardized form is well-suited to determine the dermatopharmacokinetics of topically applied substances and is used, e.g., for the determination of the homogeneity of the distribution and the ex vivo determination of a universal sun protection factor characterizing the efficacy of sunscreens.
282 citations
References
More filters
TL;DR: A procedure for photodensitometric quantitation of thin-layer chromatograms is described which can give a complete analysis of a mixture of neutral lipids in a single chromatogram without the necessity for reference mixtures.
270 citations
TL;DR: It is of considerable interest to analyze the epidermal lipids as they occur in the Malpighian layer because they may be altered in transit to the surface and may also be diluted by admixture with sebum.
183 citations
TL;DR: The results show that the composition of the sebaceous type excretion varies not only from species to species but for different anatomical sites within a given species.
Abstract: The literature is reviewed and new data are presented for the lipid class analysis of samples of lipid from the following skin tissues and appendages: Total epidermis, stratum corneum, and living epidermis from the human leg, total epidermis (human sole), total epidermis (rat body), sebaceous glands (human scalp), Meibomian glands (human eyelid), preputial glands (rat), preen gland (domestic goose), scalp skin surface (human),vernix caseosa (human fetal body), and rat skin surface from the back. Lipid yields are also given for most of these samples. The results show that the composition of the sebaceous type excretion varies not only from species to species but for different anatomical sites within a given species. Noteworthy is the striking number of unidentified components. Evidence is presented for the existence of a wax diester in the sebaceous gland excretion of the rat.
112 citations
TL;DR: The comparable variations in another constituent of sebum, cholesterol, are studied and observations on squalene are extended in a study of the possible role of this hydrocarbon in the metabolism of the skin.
Abstract: The object of our investigations has been to study the composition ofsebum and to elucidate its role in maintaining the health of the skin. In a previous paper on the hydrocarbons of sebum (Boughton, Hodgson-Jones, MacKenna, Wheatley & Wormall, 1955) we observed that the squalene content of sebum showed wide variations, both in samples collected from the same subject on different occasions and between samples collected from different subjects. This variation may be peculiar to squalene or it may indicate a variation in the overall composition of sebum. To investigate this possibility, we have, therefore, studied the comparable variations in another constituent of sebum, cholesterol, and have also extended our observations on squalene in a study of the possible role of this hydrocarbon in the metabolism of the skin. A preliminary report of part of this work has already appeared (MacKenna, Wheatley & Wormall, 1955).
66 citations
38 citations