Anchoring and length regulation of Porphyromonas gingivalis Mfa1 fimbriae by the downstream gene product Mfa2.
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Cites background or result from "Anchoring and length regulation of ..."
...…main structural pilins (FimA [major] or Mfa1 [minor]) that form the stalk of the pilus (Park et al., 2005; Sojar et al., 1991), followed by genes for the anchors pilins (FimB [major] and Mfa2 [minor]) and other ancillary pilins or regulatory elements (Hasegawa et al., 2009; Nagano et al., 2010)....
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...Consistent with previous results (Hasegawa et al., 2009), three to four times longer Mfa1 pili were produced by mutants without Mfa2, compared to WT (Figures 5D and 5E)....
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...Previous studies showed that anchor pilins (Mfa2 and FimB) of both minor and major pili from P. gingivalis are located at the pili base and regulate their length (Hasegawa et al., 2009; Nagano et al., 2010)....
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38 citations
Cites background from "Anchoring and length regulation of ..."
...Our group recently reported that Mfa2 of P. gingivalis also played a role in length regulation and cell anchoring of Mfa1 fimbriae (Hasegawa et al., 2009)....
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...gingivalis also played a role in length regulation and cell anchoring of Mfa1 fimbriae (Hasegawa et al., 2009)....
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...However, PapH/Mfa2 were copurified with each type of fimbria (Verger et al., 2006; Hasegawa et al., 2009), but we do not have experimental evidence thus far that FimB is associated with FimA fimbriae....
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33 citations
References
1,490 citations
"Anchoring and length regulation of ..." refers background in this paper
...Porphyromonas gingivalis is a Gram-negative, black-pigmented, obligate anaerobe that has been implicated in adult periodontitis (Lamont & Jenkinson, 1998; Socransky & Haffajee, 2005), which is a major cause of tooth loss in the adult population....
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1,055 citations
"Anchoring and length regulation of ..." refers background in this paper
...Fimbriae, pili or curli are adhesive hair-like organelles that project from the cell surface of a wide variety of Gramnegative as well as Gram-positive bacteria (Barnhart & Chapman, 2006; Capitani et al., 2006; Pizarro-Cerda & Cossart, 2006)....
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983 citations
"Anchoring and length regulation of ..." refers background in this paper
...Porphyromonas gingivalis is a Gram-negative, black-pigmented, obligate anaerobe that has been implicated in adult periodontitis (Lamont & Jenkinson, 1998; Socransky & Haffajee, 2005), which is a major cause of tooth loss in the adult population....
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...Fimbriae also play a major role in adhesion to and invasion of gingival epithelial cells by P. gingivalis (Andrian et al., 2006; Lamont & Jenkinson, 1998)....
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908 citations
"Anchoring and length regulation of ..." refers background in this paper
...gingivalis, and contribute to the formation of mixed-species biofilms on oral surfaces (Jenkinson & Lamont, 2005; Kolenbrander et al., 2002; Yoshimura et al., 2009)....
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...Fimbriae are one of the major colonization factors of P. gingivalis, and contribute to the formation of mixed-species biofilms on oral surfaces (Jenkinson & Lamont, 2005; Kolenbrander et al., 2002; Yoshimura et al., 2009)....
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840 citations
"Anchoring and length regulation of ..." refers background in this paper
...Fimbriae, pili or curli are adhesive hair-like organelles that project from the cell surface of a wide variety of Gramnegative as well as Gram-positive bacteria (Barnhart & Chapman, 2006; Capitani et al., 2006; Pizarro-Cerda & Cossart, 2006)....
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