Angiogenesis in life, disease and medicine
Citations
5,372 citations
Cites background from "Angiogenesis in life, disease and m..."
...Blood vessels—Networks of blood vessels are critical for transport of oxygen and nutrients to all tissues, removal of metabolic waste products, and trafficking of stem and progenitor cells, which are critical for organ growth in the embryo and wound repair in the adult [114]....
[...]
4,441 citations
Cites background from "Angiogenesis in life, disease and m..."
...Several mechanisms have been proposed to explain these phenomena, which are related to changes in the tumour cells, endothelial cells or other stromal cell...
[...]
2,845 citations
Cites background from "Angiogenesis in life, disease and m..."
...Hypoxia ensues as oxygen supplies become limited, and compensatory angiogenesis is induced through the production of various angiogenic factors in an attempt to restore the required levels of oxygen and nutrient deliver...
[...]
2,670 citations
1,990 citations
Cites background from "Angiogenesis in life, disease and m..."
...Carmeliet's prediction in the December 2005 issue of Nature...
[...]
References
12,395 citations
4,952 citations
4,137 citations
"Angiogenesis in life, disease and m..." refers background in this paper
...The formation of vessels is a complex process, requiring a finely tuned balance between numerous stimulatory and inhibitory signals, such as integrins, angiopoietins, chemokines, junctional molecules, oxygen sensors, endogenous inhibitors and many other...
[...]
3,373 citations
"Angiogenesis in life, disease and m..." refers background in this paper
...Stromal fibroblasts also recruit EPCs by releasing stromal-cell-derived factor 1α (SDF-1α...
[...]
2,923 citations