Angiotensin-converting enzymes (ACE, ACE2) gene variants and COVID-19 outcome.
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"Angiotensin-converting enzymes (ACE..." refers background in this paper
...…the SARS-CoV-2 is an Angiotensin I converting enzyme 2 (ACE2)-tropic virus, and the “spike” (S) protein of the viral envelope would thus bind to the nasopharyngeal mucosa and alveolar pneumocytes that express ACE2 at their surface (Yan et al., 2020; Shang et al., 2020; Hoffmann et al., 2020)....
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5,527 citations
4,109 citations
"Angiotensin-converting enzymes (ACE..." refers background in this paper
...Like SARS-CoV, the SARS-CoV-2 is an Angiotensin I converting enzyme 2 (ACE2)-tropic virus, and the “spike” (S) protein of the viral envelope would thus bind to the nasopharyngeal mucosa and alveolar pneumocytes that express ACE2 at their surface (Yan et al., 2020; Shang et al., 2020; Hoffmann et al., 2020)....
[...]
...…the SARS-CoV-2 is an Angiotensin I converting enzyme 2 (ACE2)-tropic virus, and the “spike” (S) protein of the viral envelope would thus bind to the nasopharyngeal mucosa and alveolar pneumocytes that express ACE2 at their surface (Yan et al., 2020; Shang et al., 2020; Hoffmann et al., 2020)....
[...]
3,360 citations