Antibacterial and antioxidant activity of methanol extract of Evolvulus nummularius.
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TL;DR: There are concerns about using synthetic phenolic antioxidants as food additives because of the reported negative effects on human health, so a replacement of these synthetics by antioxidant extractions from various foods has been proposed.
Abstract: There are concerns about using synthetic phenolic antioxidants such as butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA) as food additives because of the reported negative effects on human health. Thus, a replacement of these synthetics by antioxidant extractions from various foods has been proposed. More than 8000 different phenolic compounds have been characterized; fruits and vegetables are the prime sources of natural antioxidants. In order to extract, measure, and identify bioactive compounds from a wide variety of fruits and vegetables, researchers use multiple techniques and methods. This review includes a brief description of a wide range of different assays. The antioxidant, antimicrobial, and anticancer properties of phenolic natural products from fruits and vegetables are also discussed.
550 citations
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TL;DR: Traditional herbal medicine has flourished in rural areas where modern medicine is parsimoniously accessed because of the high cost and long travel time to health center, and the latest pharmacological findings, common Ayurvedic and earlier uses were consistent.
Abstract: Plant species have long been used as principal ingredients of traditional medicine in far-west Nepal. The medicinal plants with ethnomedicinal values are currently being screened for their therapeutic potential but their data and information are inadequately compared and analyzed with the Ayurveda and the phytochemical findings. The present study evaluated ethnomedicinal plants and their uses following literature review, comparison, field observations, and analysis. Comparison was made against earlier standard literature of medicinal plants and ethnomedicine of the same area, the common uses of the Ayurveda and the latest common phytochemical findings. The field study for primary data collection was carried out from 2006-2008. The herbal medicine in far-west Nepal is the basis of treatment of most illness through traditional knowledge. The medicine is made available via ancient, natural health care practices such as tribal lore, home herbal remedy, and the Baidhya, Ayurveda and Amchi systems. The traditional herbal medicine has not only survived but also thrived in the trans-cultural environment with its intermixture of ethnic traditions and beliefs. The present assessment showed that traditional herbal medicine has flourished in rural areas where modern medicine is parsimoniously accessed because of the high cost and long travel time to health center. Of the 48 Nepalese medicinal plants assessed in the present communication, about half of the species showed affinity with the common uses of the Ayurveda, earlier studies and the latest phytochemical findings. The folk uses of Acacia catechu for cold and cough, Aconitum spicatum as an analgesic, Aesculus indica for joint pain, Andrographis paniculata for fever, Anisomeles indica for urinary affections, Azadirachta indica for fever, Euphorbia hirta for asthma, Taxus wallichiana for tumor control, and Tinospora sinensis for diabetes are consistent with the latest pharmacological findings, common Ayurvedic and earlier uses. Although traditional herbal medicine is only a primary means of health care in far-west Nepal, the medicine has been pursued indigenously with complementing pharmacology and the Ayurveda. Therefore, further pharmacological evaluation of traditional herbal medicine deserves more attention.
185 citations
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TL;DR: Aqueous extracts of C. nudiflora has significant control over free radical scavenging activity and inhibition of the growth of food pathogenic bacteria, and the aqueous extract contains abundance of phenolics and flavonoids higher than other extracts.
Abstract: The study explored on the commonly available weed plant Commelina nudiflora which has potential in-vitro antioxidant and antimicrobial activity. The different polar solvents such as ethanol, chloroform, dichloromethane, hexane and aqueous were used for the soxhlet extraction. The extracts were identified pharmacologically as important bioactive compounds and their potential free radical scavenging activities, and antimicrobial properties were studied. C. nudiflora extracts were monitored on their in-vitro antioxidant ability by DPPH and ABTS radical scavenging assay. Aqueous extract shows significant free radical scavenging activity of 63.4 mg/GAE and 49.10 mg/g in DPPH and ABTS respectively. Furthermore, the aqueous crude extract was used in antibacterial studies, which shows the highest inhibitory activity against Pseudomonas aeruginosa, Escherichia coli and Salmonella typhi. Among all the extracts, aqueous extract of C. nudiflora has significant control over free radical scavenging activity and inhibition of the growth of food pathogenic bacteria. Also, the aqueous extract contains abundance of phenolics and flavonoids higher than other extracts. This study explored weed plant C. nudiflora as a potential source of antioxidant and antibacterial efficacy and identified various therapeutic value bioactive compounds from GC–MS analysis.
42 citations
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TL;DR: It can be concluded that antioxidant and antiageing traits of flavonoids in apple extract plus biocidal feature of silver nanoparticles can be synergistically and successfully utilized in the form of hydrogel.
Abstract: The advancement of the biological production of nanoparticles using herbal extracts performs a significant role in nanotechnology discipline as it is green and does not engage harsh chemicals. The objective of the present investigation was to extract flavonoids in the mode of apple extract and synthesize its silver nanoparticles and ultimately nanoparticles loading into hydrogels. The presence of flavonoids in apple extract was characterized by preliminary testing like dil. ammonia test and confirmatory test by magnesium ribbon test. The synthesized silver nanoparticles were characterized using UV spectroscopy, particle size and surface morphology, and zeta potential. Silver nanoparticles loaded hydrogels were evaluated for physical appearance, pH, viscosity, spreadability, porosity, in vitro release, ex vivo permeation, and antibacterial (E. coli and S. aureus) and antioxidant studies (DPPH radical scavenging assay). Well dispersed silver nanoparticles below were observed in scanning electron microscope image. Hydrogels displayed in vitro release of 98.01% ± 0.37% up to 24 h and ex vivo permeation of 98.81 ± 0.24% up to 24 h. Hydrogel effectively inhibited the growth of both microorganism indicating good antibacterial properties. The value of percent radical inhibition was 75.16% ± 0.04 revealing its high antioxidant properties. As an outcome, it can be concluded that antioxidant and antiageing traits of flavonoids in apple extract plus biocidal feature of silver nanoparticles can be synergistically and successfully utilized in the form of hydrogel.
36 citations
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Journal Article•
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TL;DR: The Society for Free Radical Research (SFRR) has decided to become a geographically regionalized organization, in which each member society will belong to the new "umbrella" or confederacy group to be called SFRR International.
Abstract: The Oxygen Society was organized on the American continent in early 1988 and adopted Free Radical Biology & Medicine as its official journal. Also during the past year the Society for Free Radical Research (SFRR) has decided to become a geographically regionalized organization, in which each member society will belong to the new "umbrella" or confederacy group to be called SFRR International.
34 citations
References
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TL;DR: In this paper, the chemical nature of the antioxidant is known and a test specific for the compound or group of interest; for example, the nitroprusside test for sulphydryl groups.
Abstract: METHODS for measuring antioxidants and appraising antioxidant activity appear to be of two general types. If the chemical nature of the antioxidant is known, one may strive for a test specific for the compound or group of interest; for example, the nitroprusside test for sulphydryl groups. Alternatively one may observe the inhibition of some natural oxidative process such as the β-oxidation of fats, as a function of the added antioxidant.
9,416 citations
"Antibacterial and antioxidant activ..." refers methods in this paper
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TL;DR: The current status of botanical screening efforts, as well as in vivo studies of their effectiveness and toxicity, are summarized and the structure and antimicrobial properties of phytochemicals are addressed.
Abstract: The use of and search for drugs and dietary supplements derived from plants have accelerated in recent years. Ethnopharmacologists, botanists, microbiologists, and natural-products chemists are combing the Earth for phytochemicals and “leads” which could be developed for treatment of infectious diseases. While 25 to 50% of current pharmaceuticals are derived from plants, none are used as antimicrobials. Traditional healers have long used plants to prevent or cure infectious conditions; Western medicine is trying to duplicate their successes. Plants are rich in a wide variety of secondary metabolites, such as tannins, terpenoids, alkaloids, and flavonoids, which have been found in vitro to have antimicrobial properties. This review attempts to summarize the current status of botanical screening efforts, as well as in vivo studies of their effectiveness and toxicity. The structure and antimicrobial properties of phytochemicals are also addressed. Since many of these compounds are currently available as unregulated botanical preparations and their use by the public is increasing rapidly, clinicians need to consider the consequences of patients self-medicating with these preparations.
6,996 citations
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TL;DR: The use of the stable free radical diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity and its application in antioxidant research is described.
Abstract: Molyneux, P. The use of the stable free radical diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity
2,225 citations
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01 Jan 1991
TL;DR: A Dictionary of Indian Folk Medicine And Ethnobotany (free) Review of Literature 28 as mentioned in this paper, in relation to health and livelihood security in district Bastar of Chhattisgarh State.
Abstract: DICTIONARY OF INDIAN FOLK MEDICINE AND ETHNOBOTANY Dictionary Of Indian Folk Medicine And Ethnobotany (FREE) Review of Literature 28 Ethnobotany in relation to health and livelihood security in district Bastar of Chhattisgarh State. medicine from Bangalore. Sat, 20 Apr 2019 11:05:00 GMT Vaccinium vitis-idaea Wikipedia Sapindus Wikipedia Sapindus is a genus of about five to twelve species of shrubs and small trees in the Lychee family, Sapindaceae, native to warm temperate to tropical regions in both the Old World and New World. Botany Plant-names ? Sinhala Plant names ?????? ??? ... Sri Lanka plant names in Sinhala, tamil, botany, ethnobotany, etymology, computer science sinhala glossary links to place names, old and new maps, philological, historical and sociological notes, links to news and events Medicinal Plants of the Russian Pharmacopoeia; their ... Ethnopharmacological relevance. Due to the location of Russia between West and East, Russian phytotherapy has accumulated and adopted approaches that originated in European and Asian traditional medicine. Who's Who of Harlans Harlan FamilyWho's Who The Harlan Connection with Mason & Dixon. Charles Mason ARS (1728-1786) was an astronomer from Gloucestershire who worked for the Astronomer Royal at Greenwich, near London. ORGANIC AND PERMACULTURE GARDENING Great Dreams The Sustainable Farming Connection. Permaculture The Earth. International Plant Genetic Resources Institute IPGRI Regional Office for Asia, the Pacific and Oceania Discovery and resupply of pharmacologically active plant ...
846 citations
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TL;DR: All the various techniques are reviewed here and, in order to unify the different criteria and parameters, standard methods to study the antimicrobial activity of medicinal plants are proposed.
Abstract: Diffusion and dilution methods have been employed to study the antimicrobial activity of medicinal plants. A number of modifications have been made in the technique in order to obtain better results. Since some factors (culture medium composition, microorganisms tested, extractive method, pH, solubility of the sample in the culture medium, etc.) can change results, it is difficult using these methods to standardize a procedure for the study of antimicrobial plants. Bioautography is another method for studying antimicrobial activity. With it, previously chromatographed principles are diffused to the agar. The results can also change according to the method employed. All the various techniques are reviewed here and, in order to unify the different criteria and parameters, standard methods to study the antimicrobial activity of medicinal plants are proposed.
800 citations
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