Antibiotic resistance and extended spectrum beta-lactamases: Types, epidemiology and treatment.
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Cites background from "Antibiotic resistance and extended ..."
...The expansion of CTX-M-type β-lactamase has not been explored much, and has been different from TEM- and SHV-type β-lactamases where the amino acid substitutions are common [89]....
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...The first TEM-type β-lactamase that demonstrated ESBL characteristics was TEM-3 [89]....
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...Many types of ESBLs are present based on the substrate and inhibitor mechanisms [89]....
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159 citations
References
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"Antibiotic resistance and extended ..." refers background in this paper
...BES-1, CME-1, VE-B-1, PER, SFO-1, and GES-1) (Bradford, 2001)....
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...The determination of whether a specific ESBL present in a clinical isolate is related to TEM and SHV enzymes is a complicated process because point mutations around the active sites of the TEM and SHV sequences have led to amino acid changes that increase the spectrum of activity of the parent enzymes, such as in TEM1, TEM2, and SHV1 (Bradford, 2001)....
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...) (Bradford, 2001)....
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2,563 citations
1,882 citations
"Antibiotic resistance and extended ..." refers background in this paper
...SHV-1 confers resistance to broad-spectrum penicillins such as ampicillin, tigecycline and piperacillin but not to the oxyimino substituted cephalosporins (Livermore, 1995)....
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...coli isolates (Livermore, 1995)....
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