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Anticancer Natural Products Targeting Immune Checkpoint Protein Network.

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TLDR
In this article, a review of regulatory effects of selected phytochemicals on immune checkpoint protein network and their combinational effectiveness with immune checkpoint inhibitors targeting tumor cells is presented, where the authors focus on regulatory effects on immunotherapy.
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This article is published in Seminars in Cancer Biology.The article was published on 2021-11-25 and is currently open access. It has received 5 citations till now. The article focuses on the topics: Immune checkpoint & Immune system.

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Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential

TL;DR: Resveratrol (RVT) is a well known phyto-chemical and is widely used in dietary supplements and botanical products as discussed by the authors , it shows a wide range of pharmacological/beneficial effects.
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Focus on immune checkpoint PD-1/PD-L1 pathway: New advances of polyphenol phytochemicals in tumor immunotherapy.

TL;DR: In this article , the authors provide new insights into the advantages of polyphenolic compounds in macroscopic regulation in the tumor microenvironment and deeply explore the clinical application prospects and challenges of their immunotherapeutic potential.
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Targeting regulated cell death with plant natural compounds for cancer therapy: A revisited review of apoptosis, autophagy‐dependent cell death, and necroptosis

TL;DR: In this article , the intricate mechanisms of apoptosis, autophagy-dependent cell death, and necroptosis in cancer were discussed and representative plant natural compounds and their derivatives were discussed.
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Focus on T cell exhaustion: new advances in traditional Chinese medicine in infection and cancer

TL;DR: Wang et al. as mentioned in this paper summarized recent advances in improving T cell exhaustion in infectious diseases and cancer with the aim of providing a comprehensive and valuable source of information on TCM as an experimental study and their role in collaboration with ICIs therapy.
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Epigenetic modification-associated molecular classification of gastric cancer.

TL;DR: In this article , an epigenetic modification-associated molecular classification of gastric cancer (GC) was developed to identify signature genes that accurately predict prognosis and the efficacy of immunotherapy.
References
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Journal ArticleDOI

Hallmarks of cancer: the next generation.

TL;DR: Recognition of the widespread applicability of these concepts will increasingly affect the development of new means to treat human cancer.
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The blockade of immune checkpoints in cancer immunotherapy

TL;DR: Preliminary clinical findings with blockers of additional immune-checkpoint proteins, such as programmed cell death protein 1 (PD1), indicate broad and diverse opportunities to enhance antitumour immunity with the potential to produce durable clinical responses.
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The basics of epithelial-mesenchymal transition

TL;DR: Processes similar to the EMTs associated with embryo implantation, embryogenesis, and organ development are appropriated and subverted by chronically inflamed tissues and neoplasias and the identification of the signaling pathways that lead to activation of EMT programs during these disease processes is providing new insights into the plasticity of cellular phenotypes.
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T cell exhaustion

TL;DR: Advances in the molecular delineation of T cell exhaustion are clarifying the underlying causes of this state of differentiation and also suggest promising therapeutic opportunities.
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