Antidiabetic Potential of Medicinal Plants and Their Active Components.
Bahare Salehi,Athar Ata,Nanjangud V. Anil Kumar,Farukh Sharopov,Karina Ramírez-Alarcón,Ana M. Ruiz-Ortega,Seyed Abdulmajid Ayatollahi,Patrick Valere Tsouh Fokou,Farzad Kobarfard,Zainul Amiruddin Zakaria,Zainul Amiruddin Zakaria,Marcello Iriti,Yasaman Taheri,Miquel Martorell,Antoni Sureda,William N. Setzer,Alessandra Durazzo,Massimo Lucarini,Antonello Santini,Raffaele Capasso,Elise Adrian Ostrander,Atta-ur-Rahman,Muhammad Iqbal Choudhary,William C. Cho,Javad Sharifi-Rad +24 more
- Vol. 9, Iss: 10, pp 551-661
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TLDR
Examples of medicinal plants with antidiabetic potential are described, with focuses on preclinical and clinical studies.Abstract:
Diabetes mellitus is one of the major health problems in the world, the incidence and associated mortality are increasing. Inadequate regulation of the blood sugar imposes serious consequences for health. Conventional antidiabetic drugs are effective, however, also with unavoidable side effects. On the other hand, medicinal plants may act as an alternative source of antidiabetic agents. Examples of medicinal plants with antidiabetic potential are described, with focuses on preclinical and clinical studies. The beneficial potential of each plant matrix is given by the combined and concerted action of their profile of biologically active compounds.read more
Citations
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Antioxidant Effects and Mechanisms of Medicinal Plants and Their Bioactive Compounds for the Prevention and Treatment of Type 2 Diabetes: An Updated Review.
TL;DR: An update of the findings from clinical research into medicinal plant therapy for T2DM is presented, finding bioactive molecules isolated from natural sources have been proven to lower blood glucose levels via regulating one or more of the following mechanisms.
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Plant-Derived Bioactives and Oxidative Stress-Related Disorders : A Key Trend towards Healthy Aging and Longevity Promotion
Bahare Salehi,Elena Azzini,Paolo Zucca,Elena Maria Varoni,Nanjangud V. Anil Kumar,Luciana Dini,Elisa Panzarini,Jovana Rajkovic,Patrick Valere Tsouh Fokou,Ilaria Peluso,Abhay Prakash Mishra,Manisha Nigam,Youssef El Rayess,Marc El Beyrouthy,William N. Setzer,Letizia Polito,Marcello Iriti,Antoni Sureda,Maria Magdalena Quetglas-Llabrés,Miquel Martorell,Natália Martins,Mehdi Sharifi-Rad,Leticia M. Estevinho,Javad Sharifi-Rad +23 more
TL;DR: The role of phytochemicals as antioxidants and pro-oxidant agents is carefully addressed, as is their therapeutic relevance in longevity, aging-related disorders, and healthy-aging promotion.
Journal ArticleDOI
Probiotics: Versatile Bioactive Components in Promoting Human Health.
Javad Sharifi-Rad,Célia F. Rodrigues,Zorica Stojanović-Radić,Marina Dimitrijević,Ana Aleksić,Katarzyna Neffe-Skocińska,Dorota Zielińska,Danuta Kołożyn-Krajewska,Bahare Salehi,Selvaraj Milton Prabu,Francine Schütz,Anca Oana Docea,Natália Martins,Daniela Calina +13 more
TL;DR: This paper provides an integrative overview of different aspects of probiotics, from human health care applications to safety, quality, and control, and one of the novelties of this review is the presentation of the beneficial effects of the administration of Probiotics as a potential adjuvant therapy in COVID-19.
Journal ArticleDOI
GC-MS analysis of phytoconstituents from Amomum nilgiricum and molecular docking interactions of bioactive serverogenin acetate with target proteins.
Narasimhamurthy Konappa,A. C. Udayashankar,Soumya Krishnamurthy,Chamanalli Kyathegowda Pradeep,Srinivas Chowdappa,Sudisha Jogaiah +5 more
TL;DR: This is the first description on the phytochemical constituents of the leaves and rhizomes of A. nilgiricum, which show pharmacological significance, as there has been no literature available yet on GC–MS andphytochemical studies of this plant species.
Journal ArticleDOI
Nanomaterials for Skin Delivery of Cosmeceuticals and Pharmaceuticals
Eliana B. Souto,Ana R. Fernandes,Carlos Martins-Gomes,Tiago E. Coutinho,Alessandra Durazzo,Massimo Lucarini,Selma B. Souto,Amélia M. Silva,Antonello Santini +8 more
TL;DR: The state of the art of nanomaterials commonly used for topical administration of active ingredients formulated in nanopharmaceuticals and nanocosmeceuticals for skin anti-aging are discussed.
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