Antioxidant supplements and semen parameters: An evidence based review
Citations
172 citations
Cites background from "Antioxidant supplements and semen p..."
...Investigators have showed that mainly selenium, coenzyme Q10 (CoQ10), and N-acetyl-cysteine can affect semen parameters by increasing testosterone and inhibin B [145]....
[...]
107 citations
77 citations
Cites background from "Antioxidant supplements and semen p..."
...In clinical contexts, the therapeutic effectiveness of antioxidant treatment for subfertile men was evident in several randomized trials (Ahmadi et al., 2016)....
[...]
65 citations
Cites background from "Antioxidant supplements and semen p..."
...Moreover, it is currently considered one of the leading causes of male infertility [19], together with the decrease in antioxidant activity and dysfunctional activity of mitochondria in spermatozoa....
[...]
...All the papers focused on this issue so far have demonstrated beneficial results of multiple antioxidants on sperm parameters [19]....
[...]
...Furthermore, recent research data point to the fact that diet is also directly associated with semen quality and that overall lifestyle plays a crucial role in maintaining proper reproductive functions [6,7,19,20]....
[...]
42 citations
Cites background from "Antioxidant supplements and semen p..."
...In a review of randomized trials of antioxidant supplementation among men with abnormal semen parameters, Ahmadi et al. noted a strong possibility of efficacy of supplementation in improving semen quality parameters (Ahmadi et al., 2016)....
[...]
...noted a strong possibility of efficacy of supplementation in improving semen quality parameters (Ahmadi et al., 2016)....
[...]
References
126 citations
"Antioxidant supplements and semen p..." refers background or result in this paper
...Furthermore, at baseline, positive correlations were found between serum Zinc and sperm concentration, motility and Inhibin B (50)....
[...]
...However, two other studies showed a significant improvement in zinc-attached ligands and semen key enzymes after zinc therapy (44, 50)....
[...]
119 citations
"Antioxidant supplements and semen p..." refers background in this paper
...Another double-blind controlled intervention by Safarinejad et al on 228 unexplained infertile men with abnormal sperm concentration, motility and morphology, showed that 28 wk treatment with ubiquinone led to improvement in sperm density, sperm motility and sperm morphology in the intervention group compared to the control group (40)....
[...]
117 citations
"Antioxidant supplements and semen p..." refers background in this paper
...Greco and Colleagues stated that two-month treatment with 1gr vitamin E and C improved ICSI success rate in patients with sperm DNA damage and reduced the level of DNA damage in these individuals (27)....
[...]
117 citations
"Antioxidant supplements and semen p..." refers background in this paper
...2013 (57) 20/ Asthenoteratozoospermia 1500 mg of LC, 60 mg vitamin C, 20...
[...]
...Therefore, administration of antioxidants can help in new medical treatments (57)....
[...]
114 citations
"Antioxidant supplements and semen p..." refers background or methods in this paper
...A meta-analysis showed that supplementing infertile men with CoQ10 does not increase live birth or pregnancy rates, but there is a global improvement in sperm parameters such as sperm concentration and motility and CoQ10 concentration in semen (8)....
[...]
...There are a number of studies that support the role of ROS in male infertility theory (8-11)....
[...]
...A meta-analysis by Lafuente showed that treatment with coenzyme Q10 led to a significant improvement in the sperm motility and density, whereas no significant improvements was observed in live birth and pregnancy rates (8)....
[...]