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Journal ArticleDOI

Application and Results of the Manchester Short Assessment of Quality of Life (Mansa)

01 Mar 1999-International Journal of Social Psychiatry (SAGE Publications)-Vol. 45, Iss: 1, pp 7-12
TL;DR: The Manchester Short Assessment of Quality of Life (MANSA) is a brief instrument for assessing quality of life focusing on satisfaction with life as a whole and with life domains and its psychometric properties appear satisfactory.
Abstract: Background Based on experiences and empirical evidence gained in studies using the Lancashire Quality of Life Profile (LQLP), the Manchester Short Assessment of Quality of Life (MANSA) has been developed as a condensed and slightly modified instrument for assessing quality of life. Its properties have been tested in a sample of community care patients.Method Fifty-five randomly selected patients on the Care Programme Approach were interviewed using the LQLP, the MANSA and the Brief Psychiatric Rating Scale.Results Correlations between subjective quality of life scores on MANSA and LQLP were all 0.83 or higher (0.94 for the satisfaction mean score). Cronbach's alpha for satisfaction ratings was 0.74, and association with psychopathology was in line with results for LQLP as reported in the literature.Conclusions The MANSA is a brief instrument for assessing quality of life focusing on satisfaction with life as a whole and with life domains. Its psychometric properties appear satisfactory.

Summary (1 min read)

Jump to: [INTRODUCTION][RESULTS] and [DISCUSSION]

INTRODUCTION

  • In the last 10 years, quality of life in people with mental illness has become a popular construct and an important outcome criterion in evaluative research.
  • Based on experiences gained in several thousand quality of life interviews and on the results of systematic studies, the authors therefore developed the Manchester Short Assessment of Quality of Life , a brief and modified version of the LQLP that has been intended to take into account all of the above mentioned shortcomings .
  • Objective questions that in previous studies have neither discriminated between settings or groups nor have been sensitive to change, were eliminated.
  • (3) Only 16 questions are to be asked every time the instrument is applied.

RESULTS

  • Fifty-five patients (19 women, 36 men) were interviewed.
  • In the MANSA, 33 patients said they did not have 'a close friend&dquo;, and 39 had not visited or been visited by a friend within the last week.

DISCUSSION

  • The high correlations of MANSA and LQLP scores suggest a concurrent validity for the MANSA in addition to a face and construct validity.
  • Internal consistency of satisfaction ratings seems reasonable, and associations with psychopathology are in line with results for the LQLP reported in the literature (Kaiser et at.
  • Thus, the MANSA appears a viable and valid instrument to obtain condensed and accurate quality of life data, and it is brief enough to be included in a minimum data set.
  • It should be taken into account, however, that the MANSA shares conceptual and methodological limitations with the LQLP and other similar instruments.
  • In evaluative studies, psychopathology should be assessed and controlled for as an influential factor.

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7-
APPLICATION
AND
RESULTS
OF
THE
MANCHESTER
SHORT
ASSESSMENT
OF
QUALITY
OF
LIFE
(MANSA)
S.
PRIEBE,
P.
HUXLEY,
S.
KNIGHT
&
S.
EVANS
SUMMARY
Background
Based
on
experiences
and
empirical
evidence
gained
in
studies
using
the
Lancashire
Quality
of
Life
Profile
(LQLP),
the
Manchester
Short
Assessment
of
Quality
of
Life
(MANSA)
has
been
developed
as
a
condensed
and
slightly
modified
instrument
for
assessing
quality
of
life.
Its
properties
have
been
tested
in
a
sample
of
community
care
patients.
Method
Fifty-five
randomly
selected
patients
on
the
Care
Programme
Approach
were
interviewed
using
the
LQLP,
the
MANSA
and
the
Brief
Psychiatric
Rating
Scale.
Results
Correlations
between
subjective
quality
of
life
scores
on
MANSA
and
LQLP
were
all
0.83
or
higher
(0.94
for
the
satisfaction
mean
score).
Cronbach’s
alpha
for
satisfaction
ratings
was
0.74,
and
association
with
psychopathology
was
in
line
with
results
for
LQLP
as
reported
in
the
literature.
Conclusions
The
MANSA
is
a
brief
instrument
for
assessing
quality
of
life
focusing
on
satisfaction
with
life
as
a
whole
and
with
life
domains.
Its
psychometric
properties
appear
satisfactory.
INTRODUCTION
In
the
last
10
years,
quality
of
life
in
people with
mental
illness
has
become
a
popular
construct
and
an
important outcome
criterion
in
evaluative
research.
Various
instruments
have
been
developed
for
measuring
it.
In
most
of
them,
satisfaction
with
life
in
general
and
with
life
domains
plays
a
central
role
and
is
assessed
on
Likert
type self
rating
scales
(Orley
et al.
1998).
Based
on
Lehman’s
original
work
in
the
US,
Oliver
et
al.
(1991/92)
established
the
Lancashire
Quality of
Life
Profile
(LQLP) which
has
been
widely used
in
Europe
(Priebe
et
al.
1995;
Oliver
et
czl.
1997).
Several
research
centres
now
have
huge
data
bases,
e.g.
in
Manchester,
Berlin, London
and
Verona.
In
samples
with
severe
mental
illness,
subjective
quality
of
life
ratings
obtained
by the
LQLP
have been
shown
to
be
sufficiently
reliable
(Kaiser
&
Priebe,
1998),
to
have
a
discriminative
ability
between
different
samples
and
treatment
settings
eft
al.
1997;
Kaiser
et
al.
1997;
Priebe
al.
1998a,b), and
to
be
sensitive
to
change (Holloway
&
Carson,
1998;
Hoffmann
et
al.
1998;
Priebe et
al.
in
press
a).
Yet,
research
has
also
revealed
some
shortcomings
of
the
LQLP:
Overall,
it
takes
approxi-
mately 30
minutes
to
administer
what
is
too
long for
some
purposes;
some
incorporated
parts
such
as
the
affect-balance-scale
assess
mainly
psychopathology
which
should
be
assessed
by
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8
specific
scales;
most
importantly,
there
are
many
items
in
the
LQLP
that
have
not
been
found
to
be
relevant
for
discriminating
between
samples
or
for
demonstrating
change.
Regarding
the
objective
variables,
there
are
various
items
with
insufficient
variance.
In
addition,
there
is
no
clear
way
to
sum
up
single
item
scores
for
each
domain
nor
has
an
overall
score
been
established.
Shortcomings
of
the
subjective
variables
in
the
LQLP
relate
to
inconsistency
in
the
language
used
i.e.
&dquo;how
do
you
feel
about ...?&dquo;
versus
’how
satisfied
are
you
with ...?&dquo;,
that
the
question
about
satisfaction
with
family
is
equivocal
because
it
is
unclear
which
part
of
the
family
is
referred
to
while
some
life
domains
are
assessed
by
one
question
and
others
by
more
than
one
question
which
complicates
statistical
analysis
and
interpretation
of
findings.
Finally,
it
was
widely
felt
that
a
question
on
the
domain
of
sexual
life
is
missing.
Based
on
experiences
gained
in
several
thousand
quality
of
life
interviews
and
on
the
results
of
systematic
studies,
we
therefore
developed
the
Manchester
Short
Assessment
of
Quality
of
Life
(MANSA),
a
brief
and
modified
version
of
the
LQLP
that
has
been
intended
to
take
into
account
all
of
the
above
mentioned
shortcomings
(see
Appendix
and
Priebe
et
al.
in
press
b).
Objective
questions
that
in
previous
studies
have
neither
discriminated
between
settings
or
groups
nor
have
been
sensitive
to
change,
were
eliminated.
Subjective
questions
were
reduced
to
one
item
per
life
domain
and
put
in
a
consistent
language
rating
patients’
satisfaction.
The
MANSA
consists
of
three
sections:
(1)
Personal
details
that
are
supposed
to
be
consistent
over
time
(date
of
birth,
gender,
ethnic
origin,
and
diagnosis).
(2)
Personal
details
that
may
potentially
vary
over
time
and
have
to
be
re-documented
if
change
has
occurred
(education;
employment
status
including
kind
of
occupation
and
working
hours
per
week;
monthly
income;
state
benefits;
living
situation
including
number
of
children,
people
the
patient
lives
with,
and
type
of
residence).
(3)
Only
16
questions
are
to
be
asked
every
time
the
instrument
is
applied.
Four
of
these
questions
are
termed
objective
and
to
be
answered
with
yes
or no.
Twelve
questions
are
strictly
subjective.
The
objective
items
assess
the
existence
of
a
&dquo;close
friend&dquo;,
number
of
contacts
with
friends
per
week,
accusation
of
a
crime
and
victimisation
of
physical
violence.
The
subjective
questions
obtain
satisfaction
with
life
as
a
whole,
job (or
sheltered
employ-
ment,
or
training/education,
or
unemployment/retirement),
financial
situation,
number
and
quality of
friendships,
leisure
activities,
accommodation,
personal safety,
people
that
the
patient lives
with
(or
living
alone),
sex
life,
relationship
with
family,
physical
health,
and
mental
health.
A
manual
outlines
explanation
of
questions and
their
operationalisation
(also
see
Priebe
et
czl.
in
press
b).
Like
in
the
LQLP,
satisfaction
is
rated
on
7-point
rating
scales
(
=
negative
extreme,
7 =
positive
extreme).
In
a
sample of
community
care
patients
we
applied
the
MANSA
and
examined
correlations
with
LQLP
scores
and
with
psychopathology.
METHOD
Data
was
collected
within
a
review
of
the
Care
Programme
Approach
and
care
management
by
the
School
of
Psychiatry
at
the
University
of Manchester.
Local
authorities
were
asked
to
select
at
random
approximately
20
patients
aged
between
18
and
65
who
are
on
the
Care
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9
Programme
Approach
and
receiving
services
under
the
Community
and
Mental
Health
legislation.
For
the
purpose
of
this
study,
quality
of
life
was
assessed
in
all
patients
who
were
interviewed
in
three
localities,
i.e.
two
inner
city
and
one
metropolitan
borough
using
the
LQLP
as
well
as
the
MANSA.
Psychopathology
was
assessed
on
the
24
item
version
of
the
Brief
Psychiatric
Rating
Scale
(BPRS;
Ventura et
al.
1993).
All
interviews
were
done
by
one
experienced
researcher
who
was
not
involved
in
the
patients’
care.
RESULTS
Fifty-five
patients
(19
women,
36
men)
were
interviewed.
Mean
s.d.)
age
of
patients
was
40.9
±
14.9
years.
The
diagnosis
was
schizophrenia
in
38
patients,
bipolar-affective
psychosis
in 8
patients,
first
or
recurrent
episode
of
depression
in
6
patients,
obsessive
compulsive
disorder
in
2
patients,
and
anxiety
disorder
in
1
patient.
Mean
BPRS
total
score
was
33.4
±
7.4.
Twenty
patients
were
from
ethnic
minorities.
One
patient
was
employed,
47
unemployed
and
7
retired.
Administration
of
the
MANSA
took
between
3
and
5
minutes.
In the
MANSA,
33
patients
said
they
did
not
have
’a
close
friend&dquo;,
and
39
had
not
visited
or
been
visited
by
a
friend
within
the
last
week.
Two
patients
each
reported
having
been
accused
of
a
crime
or
having
been
victims
of
physical
violence
within
the
last
year.
Means
of
single
satisfaction
scores
varied
between
4.09
± 1.17
(life
as
a
whole
today)
and
5.18
z
0.82
(family).
The
mean
score
of
all
satisfaction
items
was
4.56
±
0.51.
Table
1
shows
Pearson’s
correlations
between
satisfaction
ratings
in
the
MANSA
and
the
LQLP.
All
coefficients
are
above
0.82,
including
those
regarding
domains
that
are
assessed
by
two
or
more
items
in
the
LQLP
and
by
only
one
in
the
MANSA.
,
Correlations
of
MANSA
subjective
quality
of
life
mean
score
with
BPRS
total
score
was
r
=
-0.49
(p
<
0.001)
and
with
the
BPRS
sub
score
anxiety/depression
r
=
-0.42
(p
<
0.01).
Cronbach’s
alpha
for
the
satisfaction
ratings
in
MANSA
was
0.74.
Table
1
Correlations
between
satisfaction
ratings
on
LQLP
and
on
MANSA
’mean of
two
items
in
LQLP,
Zmean of
six
items
in
LQLP,
*p
=<
0.001
for
each
correlation
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10
DISCUSSION
The
high
correlations
of
MANSA
and
LQLP
scores
suggest
a
concurrent
validity
for
the
MANSA
in
addition
to
a
face
and
construct
validity.
Internal
consistency
of
satisfaction
ratings
seems
reasonable,
and
associations
with
psychopathology
are
in
line
with
results
for the
LQLP
reported
in
the
literature
(Kaiser
et
at.
1997;
Priebe et
al.
1998a,b).
Thus,
the
MANSA
appears
a
viable
and
valid
instrument
to
obtain
condensed
and
accurate
quality
of
life
data,
and
it
is
brief
enough
to
be
included
in
a
minimum
data
set.
It
should
be
taken
into
account,
however,
that
the
MANSA
shares
conceptual
and
methodological
limitations
with
the
LQLP
and
other
similar
instruments.
Although
it
assesses
some
objective
indicators
of
quality
of
life,
its
focus
is
clearly
on
subjective
ratings.
The
underlying
concept
of
quality
of
life
is
a
generic
and
not
a
disease
specific
one.
All
questions
allow
comparisons
with
the
general
population,
and
are
not
specifically
illness
or
symptom
related.
If
in
research
or
routine
evaluation
the
interest
is
in
more
specific
symptom-related
measures,
other
scales
should
be
used
in
addition
to
or
instead
of
the
MANSA.
The
same
holds
true
if
other
related
but
nevertheless
distinct
constructs
such
as
social
functioning
are
to
be
assessed.
In
evaluative
studies,
psychopathology
should
be
assessed
and
controlled
for
as
an
influential
factor.
Mean
satisfaction
scores
may
serve
as
a
non-specific
outcome
criterion.
Satisfaction
ratings
with
single
life
domains
should
be used
for
testing
domain
specific
and
a
priori
stated
hypotheses,
and
for
generating
such
hypotheses
if
mean
scores
reveal
significant
differences.
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1
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15 Sep 2005-BMJ
TL;DR: At one year's follow-up, psychotic symptoms changed favourably to a mean of 1.09 (standard deviation 1.27) with an estimated mean difference between groups of −0.31 (95% confidence interval −0-0.07, P = 0.02) in favour of integrated treatment.
Abstract: Objectives To evaluate the effects of integrated treatment for patients with a first episode of psychotic illness. Design Randomised clinical trial. Setting Copenhagen Hospital Corporation and Psychiatric Hospital Aarhus, Denmark. Participants 547 patients with first episode of schizophrenia spectrum disorder. Interventions Integrated treatment and standard treatment. The integrated treatment lasted for two years and consisted of assertive community treatment with programmes for family involvement and social skills training. Standard treatment offered contact with a community mental health centre. Main outcome measures Psychotic and negative symptoms (each scored from 0 to a maximum of 5) at one and two years' follow-up. Results At one year's follow-up, psychotic symptoms changed favourably to a mean of 1.09 (standard deviation 1.27) with an estimated mean difference between groups of –0.31 (95% confidence interval –0.55 to –0.07, P = 0.02) in favour of integrated treatment. Negative symptoms changed favourably with an estimated difference between groups of –0.36 (–0.54 to –0.17, P < 0.001) in favour of integrated treatment. At two years' follow-up the estimated mean difference between groups in psychotic symptoms was –0.32 (–0.58 to –0.06, P = 0.02) and in negative symptoms was –0.45 (–0.67 to –0.22, P < 0.001), both in favour of integrated treatment. Patients who received integrated treatment had significantly less comorbid substance misuse, better adherence to treatment, and more satisfaction with treatment. Conclusion Integrated treatment improved clinical outcome and adherence to treatment. The improvement in clinical outcome was consistent at one year and two year follow-ups.

502 citations

Journal ArticleDOI
TL;DR: There was moderate-quality evidence that ICM probably makes little or no difference in reducing death by suicide, and overall quality for clinically important outcomes using the GRADE approach, and possible risk of bias within included trials.
Abstract: Background Intensive Case Management (ICM) is a community-based package of care aiming to provide long-term care for severely mentally ill people who do not require immediate admission. Intensive Case Management evolved from two original community models of care, Assertive Community Treatment (ACT) and Case Management (CM), where ICM emphasises the importance of small caseload (fewer than 20) and high-intensity input. Objectives To assess the effects of ICM as a means of caring for severely mentally ill people in the community in comparison with non-ICM (caseload greater than 20) and with standard community care. We did not distinguish between models of ICM. In addition, to assess whether the effect of ICM on hospitalisation (mean number of days per month in hospital) is influenced by the intervention's fidelity to the ACT model and by the rate of hospital use in the setting where the trial was conducted (baseline level of hospital use). Search methods We searched the Cochrane Schizophrenia Group's Trials Register (last update search 10 April 2015). Selection criteria All relevant randomised clinical trials focusing on people with severe mental illness, aged 18 to 65 years and treated in the community care setting, where ICM is compared to non-ICM or standard care. Data collection and analysis At least two review authors independently selected trials, assessed quality, and extracted data. For binary outcomes, we calculated risk ratio (RR) and its 95% confidence interval (CI), on an intention-to-treat basis. For continuous data, we estimated mean difference (MD) between groups and its 95% CI. We employed a random-effects model for analyses. We performed a random-effects meta-regression analysis to examine the association of the intervention's fidelity to the ACT model and the rate of hospital use in the setting where the trial was conducted with the treatment effect. We assessed overall quality for clinically important outcomes using the GRADE approach and investigated possible risk of bias within included trials. Main results The 2016 update included two more studies (n = 196) and more publications with additional data for four already included studies. The updated review therefore includes 7524 participants from 40 randomised controlled trials (RCTs). We found data relevant to two comparisons: ICM versus standard care, and ICM versus non-ICM. The majority of studies had a high risk of selective reporting. No studies provided data for relapse or important improvement in mental state. 1. ICM versus standard care When ICM was compared with standard care for the outcome service use, ICM slightly reduced the number of days in hospital per month (n = 3595, 24 RCTs, MD -0.86, 95% CI -1.37 to -0.34,low-quality evidence). Similarly, for the outcome global state, ICM reduced the number of people leaving the trial early (n = 1798, 13 RCTs, RR 0.68, 95% CI 0.58 to 0.79, low-quality evidence). For the outcome adverse events, the evidence showed that ICM may make little or no difference in reducing death by suicide (n = 1456, 9 RCTs, RR 0.68, 95% CI 0.31 to 1.51, low-quality evidence). In addition, for the outcome social functioning, there was uncertainty about the effect of ICM on unemployment due to very low-quality evidence (n = 1129, 4 RCTs, RR 0.70, 95% CI 0.49 to 1.0, very low-quality evidence). 2. ICM versus non-ICM When ICM was compared with non-ICM for the outcome service use, there was moderate-quality evidence that ICM probably makes little or no difference in the average number of days in hospital per month (n = 2220, 21 RCTs, MD -0.08, 95% CI -0.37 to 0.21, moderate-quality evidence) or in the average number of admissions (n = 678, 1 RCT, MD -0.18, 95% CI -0.41 to 0.05, moderate-quality evidence) compared to non-ICM. Similarly, the results showed that ICM may reduce the number of participants leaving the intervention early (n = 1970, 7 RCTs, RR 0.70, 95% CI 0.52 to 0.95,low-quality evidence) and that ICM may make little or no difference in reducing death by suicide (n = 1152, 3 RCTs, RR 0.88, 95% CI 0.27 to 2.84, low-quality evidence). Finally, for the outcome social functioning, there was uncertainty about the effect of ICM on unemployment as compared to non-ICM (n = 73, 1 RCT, RR 1.46, 95% CI 0.45 to 4.74, very low-quality evidence). 3. Fidelity to ACT Within the meta-regression we found that i.) the more ICM is adherent to the ACT model, the better it is at decreasing time in hospital ('organisation fidelity' variable coefficient -0.36, 95% CI -0.66 to -0.07); and ii.) the higher the baseline hospital use in the population, the better ICM is at decreasing time in hospital ('baseline hospital use' variable coefficient -0.20, 95% CI -0.32 to -0.10). Combining both these variables within the model, 'organisation fidelity' is no longer significant, but the 'baseline hospital use' result still significantly influences time in hospital (regression coefficient -0.18, 95% CI -0.29 to -0.07, P = 0.0027). Authors' conclusions Based on very low- to moderate-quality evidence, ICM is effective in ameliorating many outcomes relevant to people with severe mental illness. Compared to standard care, ICM may reduce hospitalisation and increase retention in care. It also globally improved social functioning, although ICM's effect on mental state and quality of life remains unclear. Intensive Case Management is at least valuable to people with severe mental illnesses in the subgroup of those with a high level of hospitalisation (about four days per month in past two years). Intensive Case Management models with high fidelity to the original team organisation of ACT model were more effective at reducing time in hospital. However, it is unclear what overall gain ICM provides on top of a less formal non-ICM approach. We do not think that more trials comparing current ICM with standard care or non-ICM are justified, however we currently know of no review comparing non-ICM with standard care, and this should be undertaken.

311 citations

Journal ArticleDOI
05 Apr 2012-BMJ
TL;DR: Cognitive therapy plus monitoring did not significantly reduce transition to psychosis or symptom related distress but reduced the severity of psychotic symptoms in young people at high risk of psychosis.
Abstract: Objective To determine whether cognitive therapy is effective in preventing the worsening of emerging psychotic symptoms experienced by help seeking young people deemed to be at risk for serious conditions such as schizophrenia.

293 citations

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TL;DR: There is a need for further research and development of the Lancashire Quality of Life Profile, in particular with reference to the consequences of the use of the profile as a routine monitoring instrument and the most appropriate form of statistical analysis in longitudinal data-sets.
Abstract: Quality of life (QOL) has become an important outcome measure for many disorders, including mental illness. The Lancashire Quality of Life Profile (LQOLP) was developed for use in operational contexts, and has been translated into several languages. It is in use in several European and North American community psychiatric services. The present paper addresses the questions: how easy is it to use?; how reliable is it?; do the results of the LQOLP vary by setting in a meaningful way?; how do the results co-vary with measures of clinical symptoms and social functioning?; how well does it measure change?; is it clinically useful? While most of the answers to these questions are favourable, there is a need for further research and development of the profile, in particular with reference to the consequences of the use of the profile as a routine monitoring instrument and the most appropriate form of statistical analysis in longitudinal data-sets.

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TL;DR: The quality of life (QOL) of the mentally ill is now becoming a more valued assessment, not just in psychiatry but in many branches of medicine, particularly those dealing with patients who suffer or are disabled over relatively long periods of time.
Abstract: The quality of life (QOL) of the mentally i l l has been a matter of concern for centuries. The great reforms to the madhouses were prompted by this, so too was the creation of asylums and most recently, the move from institutional to community care. Despite these humanitarian concerns, little effort was made to define or measure such changes in QOL. QOL is now becoming a more valued assessment, not just in psychiatry but in many branches of medicine, particularly those dealing with patients who suffer or are disabled over relatively long periods of time. Of particular note has been its use in the assessment of those being treated for cancer (Maguire & Selby, 1989). Over the years, QOL assessment came to mean taking account of anything beyond mortality and symtom levels. Even noting side-effects of treatments has been put forward as a QOL assessment. More and more, however, QOL has come to embody the justified concern for patients as people and not just cases. It has also come to reflect the rise of a more consumeroriented approach to medical care, in which the patients' own opinion of what is happening to them is taken as important, rather than patients being the objects of expert attention from professionals who themselves judge the effectiveness and relevance of what they do (Gill & Feinstein, 1994). The interest in QOL also reflects a more serious concern for that broad definition of health as \"a state of complete physical, mental and social wellbeing and not merely the absence of disease\" (World Health Organization, 1948). Virtually all the efforts of the health sector are directed towards creating an absence of disease, by prevention or treatment, with well-being as a secondary product. Without definitions and measures of well-being, however, there can be little progress towards including it as an objective in the creation of a more healthy society. QOL measures provide one step towards such a goal. WORLD HEALTH ORGANIZATION

205 citations

Journal ArticleDOI
TL;DR: It is suggested that work is associated with a markedly better quality of life for people with schizophrenia, but that disability pension programs in the United States might introduce work disincentives.
Abstract: This study examines attitudes toward work, work incentives, and the impact of work on quality of life for people with schizophrenia, and investigates whether these findings differ among Western countries We interviewed 24 randomly selected subjects with schizophrenia and schizoaffective disorder (12 employed and 12 unemployed) at each of three sites: Boulder, Colorado, United States; Berlin, Germany; and Berne, Switzerland No significant differences were found in the subjects' attitudes toward work or subjective well-being, although Swiss patients had a higher cost-of-living-adjusted income Unemployed subjects reported a lower subjective reservation (minimum financially worthwhile) wage than employed subjects in Berlin and Berne, whereas the reverse was true in Boulder When subjects from all sites were combined, employed patients displayed less psychopathology and significant advantages in terms of objective and subjective measures of income and well-being: They were also more likely to stress the importance of work The results suggest that work is associated with a markedly better quality of life for people with schizophrenia, but that disability pension programs in the United States might introduce work disincentives

162 citations