Journal ArticleDOI
Application of lipases in kinetic resolution of racemates.
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TLDR
This review article focuses on some of the recent developments in the rapidly growing field of lipase-catalyzed kinetic resolution of racemates as a versatile method for the separation of enantiomers.About:
This article is published in Chirality.The article was published on 2005-01-01. It has received 242 citations till now. The article focuses on the topics: Kinetic resolution.read more
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Lipase from Thermomyces lanuginosus: Uses and prospects as an industrial biocatalyst
TL;DR: The main uses of the lipase from Thermomyces laguginosus will be revised, with special emphasis in the modification of fats and oils, production of biodiesel, resolution of racemic mixtures, enantioselective hydrolysis of prochiral esters and regioselectives process involving sugar preparations.
Journal ArticleDOI
Recyclable stereoselective catalysts.
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Structure control of polysaccharide derivatives for efficient separation of enantiomers by chromatography
Tomoyuki Ikai,Yoshio Okamoto +1 more
TL;DR: Direct chiral separation using chiral stationary phases for high-performance liquid chromatography (HPLC) has significantly evolved during the past few decades and is recognized as the most popular and reliable tool for both the analysis of enantiomer compositions and the preparation of pure enantiomers.
Journal ArticleDOI
Trends in lipase-catalyzed asymmetric access to enantiomerically pure/enriched compounds
TL;DR: A review of the recent developments in the rapidly growing field of lipase-catalyzed asymmetric access to enantiomerically pure/enriched compounds can be found in this article.
Journal ArticleDOI
Membranes and membrane processes for chiral resolution
TL;DR: This critical review is devoted to an active field of research on chiral separation, membrane-based enantioseparation technique, which has potential for large-scale production of single-enantiomer compounds.
References
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Book
Stereochemistry of Organic Compounds
TL;DR: Stereochemistry of Alkenes Conformation of Acyclic Molecules Configuration and conformation of cyclic Molecule Stereoselective Synthesis Chiroptical Properties Chirality in Molecules Devoid of Chiral Centres as discussed by the authors.
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Industrial biocatalysis today and tomorrow
TL;DR: Biocatalytic processes can now be carried out in organic solvents as well as aqueous environments, so that apolar organic compounds aswell as water-soluble compounds can be modified selectively and efficiently with enzymes and bioc atalytically active cells.
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Improving enzymes by using them in organic solvents
TL;DR: The technological utility of enzymes can be enhanced greatly by using them in organic solvents rather than their natural aqueous reaction media, and they have found numerous potential applications, some of which are already commercialized.
Journal ArticleDOI
Industrial Methods for the Production of Optically Active Intermediates
Michael Breuer,Klaus Ditrich,Tilo Habicher,Bernhard Hauer,Maria Kesseler,Rainer Stürmer,Thomas Zelinski +6 more
TL;DR: For the industrial implementation of many transformations alternative methods are available and the advantages of the individual methods will be discussed herein and exemplified by syntheses of relevant compounds.
Journal ArticleDOI
Lipases: Interfacial Enzymes with Attractive Applications.
Rolf D. Schmid,Robert Verger +1 more
TL;DR: Reactions based on lipase catalysis usually proceed with high regio- and enantioselectivity, and the Ca2+ antagonist diltiazem was obtained with lipase from Serratia marcescens.