Journal ArticleDOI
Are conventional sperm morphology and motility assessments of predictive value in subfertile men
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TLDR
The results indicate that sperm morphology as currently assessed may not be important in predicting fertility in subfertile men with a mean sperm concentration over 5 million/ml and the % sperm motility may only be a relevant predictor in oligospermic men.Abstract:
Sperm morphology and motility are believed to be important prognostic factors for fertility. Results of a group of 67 men investigated for primary infertility who had mean sperm concentrations greater than 5 million per ml and who later produced pregnancies, were compared with those of 67 matched controls who remained infertile. All female partners were potentially fertile. The groups were matched for other known prognostic factors for fertility, namely, wife's age, the duration of infertility, sperm concentration and varicocele size. There were no significant differences between the two groups overall in the (mean +/- SEM)% of sperm with normal morphology (58.3 +/- 2.1; 58.5 +/- 2.2), or motility (40.6 +/- 1.8; 37.0 +/- 2.0). However, among oligospermic men from the two groups, sperm motility was significantly higher (P less than 0.05) in the subsequently fertile group (43.1 +/- 2.6%) than in the persistently infertile group (33.3 +/- 3.7). These results indicate that sperm morphology as currently assessed may not be important in predicting fertility in subfertile men with a mean sperm concentration over 5 million/ml and the % sperm motility may only be a relevant predictor in oligospermic men.read more
Citations
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Journal ArticleDOI
Computer assisted semen analyzers in andrology research and veterinary practice
TL;DR: Although some interesting results, mainly in humans, have already been obtained, many questions remain, which have to be answered to allow for further development of this technology in veterinary medicine, clinical fertility settings, physiological and toxicology research activities.
Journal ArticleDOI
Male factors and the likelihood of pregnancy in infertile couples. I. Study of sperm characteristics
TL;DR: Multivariate analysis showed that the best prognostic indicator of fertility was given by the percentage of motile sperm and the Multiple Anomalies Index, particularly in patients with primary infertility.
Journal ArticleDOI
Effect of male age on fertility: evidence for the decline in male fertility with increasing age
TL;DR: Evidence for and quantification of the decline in men's fertility with increasing age is provided using age at the onset of pregnancy attempts, adjusting for the confounding effects of women's age, coital frequency, and life-style characteristics.
Journal ArticleDOI
Semen parameters in a fertile versus subfertile population: a need for change in the interpretation of semen testing
Willem Ombelet,Eugene Bosmans,M. Janssen,A. Cox,Jos Vlasselaer,Wilfried Gyselaers,Hubert Vandeput,Jan Gielen,Hans Pollet,Michael Maes,Omer Steeno,Thinus F. Kruger +11 more
TL;DR: In this article, a prospectively designed study was conducted to compare a fertile and a subfertile population so as to define normal values for different semen parameters, including sperm morphology.
Journal ArticleDOI
Tests of human sperm function and fertilization in vitro
TL;DR: Results of in vitro fertilization can be used to evaluate tests of human sperm function and Logistic regression analysis is a powerful method for determining which groups of sperm characteristics are independently related to fertilization rates.
References
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Book ChapterDOI
Current Status and Future Prospects
TL;DR: In this chapter, the present position of IVF and ET in infertility based on tubal, male factor and undiscovered causes (idiopathic) is discussed and there will be very rapid progress in the future, and thus some trends in research and extensions ofIVF are covered.
Journal ArticleDOI
Standards for investigation of human semen Untersuchungsstandards für das menschliche Sperma La standardisation de l'analyse du sperme humain
TL;DR: A proposal for standardization of the analyses of human semen is presented with special emphasis on the necessity to perform accurate evaluation of sperm morphology, to determine the percentage of dead cells and to carry out biochemical analyses of the seminal plasma to evaluate the secretory function of the accessory genital glands.
Journal ArticleDOI
The influence of seminal characteristics on the success rate of human in vitro fertilization.
TL;DR: The relationship of conventional semen parameters and the limits of these parameters for fertilization in vitro were analyzed from data over a 3-year period (1980 to 1982) as mentioned in this paper, where sperm motility was the single most important parameter determining the fertilization rate.
Journal ArticleDOI
An analysis of sperm function in cases of unexplained infertility: conventional criteria, movement characteristics, and fertilizing capacity
R. John Aitken,Fiona S.M. Best,David W. Richardson,Ovrang Djahanbakhch,David Mortimer,A. Alan Templeton,Martin M. Lees +6 more
TL;DR: Of the conventional parameters of semen analysis examined, the most revealing was the morphologic character of the sperm, which was significantly poorer in the group with unexplained infertility than in the normal fertile control group and also showed a significant relationship with the presence of subnormal fertilizing capacity in the hamster egg assay.