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Are deep eutectic solvents benign or toxic

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TLDR
It was found that the cytotoxicity of DESs was much higher than their individual components (e.g. glycerine, ChCl) indicating that their toxicological behavior is different.
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This article is published in Chemosphere.The article was published on 2013-02-01. It has received 434 citations till now. The article focuses on the topics: Deep eutectic solvent.

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Natural Deep Eutectic Solvents – Solvents for the 21st Century

TL;DR: Deep Eutectic Solvents (DES) as discussed by the authors are a class of solvents that can be defined as a mixture of two or more components, which at a particular composition present a high melting point depression becoming liquids at room temperature.
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Green and Sustainable Solvents in Chemical Processes

TL;DR: This Review considers several aspects of the most prominent sustainable organicsolvents in use today, ionic liquids, deep eutectic solvents, supercritical fluids, switchable solVents, liquid polymers, and renewable solvent, giving a more complete picture of the current status of sustainable solvent research and development.
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Deep Eutectic Solvents: Physicochemical Properties and Gas Separation Applications

TL;DR: Deep eutectic solvents (DESs) have been considered as alternatives to ILs that maintain most of their relevant properties, such as task-specific character, and at the same time avoid some of their problems, mainly from economic and environmental viewpoints as discussed by the authors.
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Natural Deep Eutectic Solvents: Properties, Applications, and Perspectives.

TL;DR: This review focuses on NADES properties and applications in NP research and identifies potential areas for future studies of (NA)DES by evaluating relevant applications, including their use as extraction and chromatographic media as well as their biomedical relevance.
References
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Journal ArticleDOI

Deep eutectic solvents: syntheses, properties and applications

TL;DR: All works discussed in this review aim at demonstrating that Deep Eutectic Solvents not only allow the design of eco-efficient processes but also open a straightforward access to new chemicals and materials.
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Deep Eutectic Solvents Formed between Choline Chloride and Carboxylic Acids: Versatile Alternatives to Ionic Liquids

TL;DR: It is shown that the conductivity and viscosity of these liquids is controlled by ion mobility and the availability of voids of suitable dimensions, and this is consistent with the fluidity of other ionic liquids and molten salts.
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Characterization of thermal behavior of deep eutectic solvents and their potential as drug solubilization vehicles.

TL;DR: Deep eutectic solvent can be a promising vehicle for increasing exposure of poorly soluble compounds in preclinical studies and in solubility in DES is 5 to 22,000 folds more than that in water.
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A novel technique for separating glycerine from palm oil-based biodiesel using ionic liquids

TL;DR: In this paper, a quaternary ammonium salt-glycerine-based ionic liquid is proposed as a solvent for extracting glycerine from the transesterification biodiesel product.
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