Journal ArticleDOI
Association between premature mortality and hypopituitarism
Jeremy W. Tomlinson,N. Holden,Robert Kerrin Hills,Keith Wheatley,Richard N. Clayton,A. S. Bates,Michael C. Sheppard,Paul M. Stewart +7 more
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TLDR
Age at diagnosis, female sex, and above all, craniopharyngioma were significant independent risk factors and specific endocrine-axis deficiency, with the exception of untreated gonadotropin deficiency, does not seem to have a role.About:
This article is published in The Lancet.The article was published on 2001-02-10. It has received 912 citations till now. The article focuses on the topics: Population & Hypopituitarism.read more
Citations
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Clinical practice guidelines for multiple endocrine neoplasia type 1 (MEN1)
Rajesh V. Thakker,Paul J. Newey,Gerard V Walls,John P. Bilezikian,Henning Dralle,Peter R. Ebeling,Shlomo Melmed,Akihiro Sakurai,Francesco Tonelli,Maria Luisa Brandi +9 more
TL;DR: It is recommended that MEN1 patients and their families should be cared for by multidisciplinary teams comprising relevant specialists with experience in the diagnosis and treatment of patients with endocrine tumors.
Journal ArticleDOI
Evaluation and Treatment of Adult Growth Hormone Deficiency: An Endocrine Society Clinical Practice Guideline
TL;DR: GH therapy offers benefits in body composition, exercise capacity, skeletal integrity, and quality of life measures and is most likely to benefit those patients who have more severe GHD, and the risks associated with GH treatment are low.
Journal ArticleDOI
Prevalence of pituitary adenomas: a community‐based, cross‐sectional study in Banbury (Oxfordshire, UK)
TL;DR: The resource allocation for PAs in the health care system is lacking a reliable and an up‐to‐date epidemiological background that would reflect the recent advances in the diagnostic technologies, leading to the earlier recognition of these tumours.
Journal ArticleDOI
Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategies.
Bianca C. Bernardo,Kate L. Weeks,Kate L. Weeks,Lynette Pretorius,Lynette Pretorius,Julie R. McMullen +5 more
TL;DR: Molecular mechanisms associated with features of cardiac hypertrophy, including protein synthesis, sarcomeric organization, fibrosis, cell death and energy metabolism are discussed and a summary of profiling studies that have examined genes, microRNAs and proteins that are differentially expressed in models of pathological and physiologicalhypertrophy is provided.
Journal ArticleDOI
Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer
Gary L. Francis,Steven G. Waguespack,Andrew J. Bauer,Peter Angelos,Salvatore Benvenga,Janete M. Cerutti,Catherine A. Dinauer,Jill Hamilton,Ian D. Hay,Markus Luster,Marguerite T. Parisi,Marianna Rachmiel,Geoffrey B. Thompson,Shunichi Yamashita +13 more
TL;DR: These inaugural guidelines provide recommendations for the evaluation and management of thyroid nodules in children and adolescents, including the role and interpretation of ultrasound, fine-needle aspiration cytology, and the management of benign nodules.
References
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Journal ArticleDOI
Premature mortality due to cardiovascular disease in hypopituitarism.
Thord Rosén,Bengt-Åke Bengtsson +1 more
TL;DR: The observations indicate that life expectancy is shortened in patients with hypopituitarism, and growth-hormone deficiency could be a factor in this increased mortality from cardiovascular disease.
Journal ArticleDOI
Low Serum Thyrotropin Concentrations as a Risk Factor for Atrial Fibrillation in Older Persons
Clark T. Sawin,Andrew I. Geller,Philip A. Wolf,Albert J. Belanger,Errol Baker,Pamela Bacharach,Peter W.F. Wilson,Emelia J. Benjamin,Ralph B. D'Agostino +8 more
TL;DR: Among people 60 years of age or older, a low serum thyrotropin concentration is associated with a threefold higher risk that atrial fibrillation will develop in the subsequent decade.
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Mortality and Cancer Incidence in Acromegaly: A Retrospective Cohort Study
TL;DR: Mortality rates due to colon cancer, all malignant disease, cardiovascular disease and overall mortality were increased with higher posttreatment GH leve...
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The natural history of Cushing's syndrome.
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Epidemiology and long-term survival in acromegaly. A study of 166 cases diagnosed between 1955 and 1984.
TL;DR: In 1985, a follow-up investigation was performed of all patients with acromegaly seen over a 30-year period at the Endocrine Unit, referral centre for the western region of Sweden, and the observed number of deaths from vascular and malignant disorders was 32 and 15, respectively, compared to the expected numbers.
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Premature mortality due to cardiovascular disease in hypopituitarism.
Thord Rosén,Bengt-Åke Bengtsson +1 more