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Asymmetric Transformations Catalyzed by Enzymes in Organic Solvents

Alexander M. Klibanov
- 24 Jul 1990 - 
- Vol. 21, Iss: 30
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This article is published in ChemInform.The article was published on 1990-07-24. It has received 43 citations till now.

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Enzymes as Green Catalysts for Precision Macromolecular Synthesis

TL;DR: The enzymatic polymerizations allowed the first in vitro synthesis of natural polysaccharides having complicated structures like cellulose, amylose, xylan, chitin, hyaluronan, and chondroitin, and producing minimal byproducts.
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Enzymatic esterification in organic media: role of water and organic solvent in kinetics and yield of butyl butyrate synthesis

TL;DR: The results allow the conclusion that the reaction took place in a phase consisting of either solid hydrated enzyme with no discrete aqueous phase or of an aqueously enzyme solution byBasically similar mechanisms according to the amount of water available to the system, the esterification being driven to completion by transfer of the esters into the organic phase because of a favourable partition coefficient.
Journal ArticleDOI

Biocatalysis in non-conventional media: Medium engineering aspects (Technical Report)

TL;DR: It has become clear that biocatalysts are not so sensitive as expected and can function under harsh conditions, such as extreme pH, temperatures and pressures, high salt concentrations, or in the presence of other additives.
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Biotechnological application of Pseudomonas aeruginosa lipase: efficient kinetic resolution of amines and alcohols

TL;DR: Results demonstrated that P. aeruginosa lipase is an extremely useful enzyme for application in synthetic organic chemistry.
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Use of ionic liquids in a lipase-facilitated supported liquid membrane.

TL;DR: There were marked differences in the permeate fluxes of various organic acids due to the substrate specificity of the lipases, particularly in the case ofphenoxybutyric acid.
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