Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America
Citations
8,695 citations
1,493 citations
Cites background from "Bad bugs, no drugs: no ESKAPE! An u..."
...This also explains the increasing antimicrobial resistance of nosocomial Gram-negative bacteria to extended-spectrum cephalosporin, a class of the newest andmost powerful antibiotics [4]....
[...]
...For example, drugresistant infections in hospitals and in the communities caused by both Gram-positive and Gram-negative bacterial pathogens are growing [4], and the continued evolution of antimicrobial resistance threatens human health by seriously compromising our ability to treat serious infections [5]....
[...]
1,467 citations
Cites background from "Bad bugs, no drugs: no ESKAPE! An u..."
...Quinolones topoisomerase ii and iv Cinoxacin, nalidixic acid (58), pipemidic acid, ciprofloxacin (59), enoxacin, gatifloxacin, gemifloxacin,levofloxacin (60), lomefloxacin, moxifloxacin, norfloxacin, ofloxacin, sparfloxacin...
[...]
...Nalidixic acid (58), the first quinolone, was discovered in 1962....
[...]
1,114 citations
901 citations
References
4,256 citations