Basilar artery occlusion
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Cites background from "Basilar artery occlusion"
...In the past, many case series and smaller studies investigated the role of endovascular stroke treatment (EVT) in BA occlusion, as recently reviewed by Mattle et al.(2) Most studies are characterized by either small patient samples, heterogeneous treatment approaches, the use of outdated EVT techniques (ie, intra-arterial thrombolysis without mechanical recanalization), or the use of first-generation mechanical recanalization devices (MERCI retriever, Penumbra device)....
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...In the past, many case series and smaller studies investigated the role of endovascular stroke treatment (EVT) in BA occlusion, as recently reviewed by Mattle et al.2 Most studies are characterized by either small patient samples, heterogeneous treatment approaches, the use of outdated EVT techniques (ie, intra-arterial thrombolysis without mechanical recanalization), or the use of first-generation mechanical recanalization devices (MERCI retriever, Penumbra device)....
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220 citations
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Cites background from "Basilar artery occlusion"
...Recanalization rates, however, are low, particularly in patients suffering from major occlusions, and majority of patients with basilar artery occlusion do not clinically benefit from intravenous thrombolysis.(39,41) On the other hand, endovascular treatment of acute ischemic stroke results in remarkably higher recanalization rates than intravenous thrombolysis, and recently published RCTs have shown strong treatment effects on clinical outcomes in patients treated interventionally for anterior circulation stroke (ie, excluding basilar arty occlusion)....
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...For instance, basilar artery occlusion is a devastating disease leading to death in up to 90% of untreated acute ischemic stroke patients, and there is still uncertainty about its preferred treatment regimen.(39) Intravenous thrombolysis with tissue plasminogen activator constitutes the only approved therapy for acute ischemic stroke that prevents patients from permanent disability and death when initiated within 4....
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References
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