Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
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...CL1 6 and CL23 of the established HA-Baxa clones were cotransfected with a spleen focusforming virus hBcl-2 vector (Hockenbery et al., 1990) and an expression vector (LAP 267) providing a hygromycin selection marker (Bairn et al....
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...Bcl-2 Coprecipitates with a 21 kd Protein Coimmunoprecipitation experiments were performed utilizing the 6C6 monoclonal antibody (MAb) that is specific for human 6~1-2 (Hockenbery et al., 1990)....
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...Bcl-2 conferred a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal (Vaux et al., 1988; Hockenbery et al., 1990; Nuriez et al., 1990)....
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...Antibodies 6C8 human B&P-specific hamster MAb (Hockenbery et al., 1990) 12CA5 influenza virus hemagglutinin protein epitope-specific murine MAb (Kolodziej and Young, 1991) and 3Fll murine Bcl-2-specific hamster MAb (veis et al....
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...In the absence of IL-3, FL512 dies by apoptosis, but overexpression of Bcl-2 extends its survival (Hockenbery et al., 1990; Nufiez et al., 1990)....
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Cites background from "Bcl-2 is an inner mitochondrial mem..."
...The cellular organelle for a prominent role in apoptosis (Hockenbery et al., 1990)....
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