Better tests, better care: improved diagnostics for infectious diseases.
Angela M. Caliendo,David N. Gilbert,David N. Gilbert,Christine C. Ginocchio,Kimberly E. Hanson,Larissa S May,Thomas C. Quinn,Thomas C. Quinn,Fred C. Tenover,David Alland,Anne J. Blaschke,Robert A. Bonomo,Karen C. Carroll,Mary Jane Ferraro,Lisa R. Hirschhorn,W. Patrick Joseph,Tobi Karchmer,Ann T MacIntyre,L. Barth Reller,Audrey F. Jackson +19 more
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TLDR
The current diagnostic landscape, including unmet needs and emerging technologies, and the challenges to the development and clinical integration of improved tests are reviewed, and recommendations that address a host of identified barriers are presented.Abstract:
In this IDSA policy paper, we review the current diagnostic landscape, including unmet needs and emerging technologies, and assess the challenges to the development and clinical integration of improved tests. To fulfill the promise of emerging diagnostics, IDSA presents recommendations that address a host of identified barriers. Achieving these goals will require the engagement and coordination of a number of stakeholders, including Congress, funding and regulatory bodies, public health agencies, the diagnostics industry, healthcare systems, professional societies, and individual clinicians.read more
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Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia the official statement of the American Thoracic Society and the Infectious Disease Society of America (特集 救急診療ガイドライン) -- (海外のガイドライン)
TL;DR: The Methodology used to Prepare the Guideline Epidemiology Incidence Etiology and Recommendations for Assessing Response to Therapy Suggested Performance Indicators is summarized.
Journal ArticleDOI
Community-acquired pneumonia requiring hospitalization among U.S. adults
Seema Jain,Derek J. Williams,Sandra R. Arnold,Krow Ampofo,Anna M. Bramley,Carrie Reed,Chris Stockmann,Evan J. Anderson,Carlos G. Grijalva,Wesley H. Self,Yuwei Zhu,Anami Patel,Weston Hymas,James D. Chappell,Robert A. Kaufman,J. Herman Kan,David Dansie,Noel Lenny,David R. Hillyard,Lia M. Haynes,Min Z. Levine,Stephen Lindstrom,Jonas M. Winchell,Jacqueline M. Katz,Dean D. Erdman,Eileen Schneider,Lauri A. Hicks,Richard G. Wunderink,Kathryn M. Edwards,Andrew T. Pavia,Jonathan A. McCullers,Lyn Finelli +31 more
TL;DR: The incidence of community-acquired pneumonia requiring hospitalization was highest among the oldest adults and despite current diagnostic tests, no pathogen was detected in the majority of patients.
Journal ArticleDOI
Phage Therapy in the Postantibiotic Era
TL;DR: The benefits of phage therapy beyond the clinical perspective are discussed, including opportunities for scientific outreach and effective education, interdisciplinary collaboration, cultural and economic growth, and even innovative use of social media, making the case thatphage therapy is more than just an alternative to antibiotics.
Journal ArticleDOI
Randomized Trial of Rapid Multiplex Polymerase Chain Reaction–Based Blood Culture Identification and Susceptibility Testing
Ritu Banerjee,Christine B Teng,Scott A. Cunningham,Sherry M. Ihde,James M. Steckelberg,James P. Moriarty,Nilay Shah,Jayawant N. Mandrekar,Robin Patel +8 more
TL;DR: A prospective randomized controlled trial evaluating outcomes associated with rapid multiplex PCR detection of bacteria, fungi, and resistance genes directly from positive BCBs found that rmPCR reported with templated comments reduced treatment of contaminants and use of broad-spectrum antimicrobials.
Journal ArticleDOI
2017 Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Management of Infectious Diarrhea.
Andi L. Shane,Rajal K. Mody,John A. Crump,Phillip I. Tarr,Theodore S. Steiner,Karen L. Kotloff,Joanne M. Langley,Christine Wanke,Cirle A. Warren,Allen C. Cheng,Joseph B. Cantey,Larry K. Pickering +11 more
TL;DR: These guidelines are intended for use by healthcare professionals who care for children and adults with suspected or confirmed infectious diarrhea and are not intended to replace physician judgement regarding specific patients or clinical or public health situations.
References
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Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012.
R. P. Dellinger,Mitchell M. Levy,Andrew Rhodes,Djillali Annane,Herwig Gerlach,Steven M. Opal,Jonathan E. Sevransky,Charles L. Sprung,Ivor S. Douglas,Roman Jaeschke,Tiffany M. Osborn,Mark E. Nunnally,Konrad Reinhart,Ruth M. Kleinpell,Derek C. Angus,Clifford S. Deutschman,Flávia Ribeiro Machado,Gordon D. Rubenfeld,Steven A R Webb,Richard Beale,Jean Louis Vincent,Rui Moreno +21 more
TL;DR: An update to the “Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock,” last published in 2008 is provided.
Journal ArticleDOI
Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults
Lionel A. Mandell,Richard G. Wunderink,Antonio Anzueto,John G. Bartlett,G. Douglas Campbell,Nathan C. Dean,Nathan C. Dean,Scott F. Dowell,Daniel M. Musher,Daniel M. Musher,Michael S. Niederman,Michael S. Niederman,Antoni Torres,Cynthia G. Whitney,Michael E. DeBakey Veterans +14 more
TL;DR: This work presents a meta-analyses of the immune system’s response to chronic obstructive pulmonary disease and shows clear patterns of decline in the immune systems of elderly patients with compromised immune systems.
Journal ArticleDOI
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock.
Anand Kumar,Daniel Roberts,Kenneth E. Wood,Bruce Light,Joseph E. Parrillo,Satendra Sharma,Robert Suppes,Daniel Feinstein,Sergio Zanotti,Leo Taiberg,David A. Gurka,Aseem Kumar,Mary Cheang +12 more
TL;DR: Effective antimicrobial administration within the first hour of documented hypotension was associated with increased survival to hospital discharge in adult patients with septic shock.
Journal ArticleDOI
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008.
R. Phillip Dellinger,Mitchell M. Levy,J. Carlet,Julian Bion,Margaret M. Parker,Roman Jaeschke,Konrad Reinhart,Derek C. Angus,Christian Brun-Buisson,Richard Beale,Thierry Calandra,JF Dhainaut,Herwig Gerlach,Maurene A. Harvey,John J. Marini,John C. Marshall,Marco Ranieri,Graham Ramsay,Jonathan E. Sevransky,B. Taylor Thompson,Sean R. Townsend,Jeffrey S. Vender,Janice L. Zimmerman,Jean Louis Vincent +23 more
TL;DR: In this paper, the authors provide an update to the original Surviving Sepsis Campaign clinical management guidelines for management of severe sepsis and septic shock, published in 2004.
Surviving sepsis campaign: international guidelines for the management of severe sepsis and septic shock: 2008
TL;DR: To provide an update to the original Surviving Sepsis Campaign clinical management guidelines, the GRADE system was used to guide assessment of quality of evidence from high (A) to very low (D) and to determine the strength of recommendations.
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Community-acquired pneumonia requiring hospitalization among U.S. adults
Seema Jain,Derek J. Williams,Sandra R. Arnold,Krow Ampofo,Anna M. Bramley,Carrie Reed,Chris Stockmann,Evan J. Anderson,Carlos G. Grijalva,Wesley H. Self,Yuwei Zhu,Anami Patel,Weston Hymas,James D. Chappell,Robert A. Kaufman,J. Herman Kan,David Dansie,Noel Lenny,David R. Hillyard,Lia M. Haynes,Min Z. Levine,Stephen Lindstrom,Jonas M. Winchell,Jacqueline M. Katz,Dean D. Erdman,Eileen Schneider,Lauri A. Hicks,Richard G. Wunderink,Kathryn M. Edwards,Andrew T. Pavia,Jonathan A. McCullers,Lyn Finelli +31 more