Betulin Is a Potent Anti-Tumor Agent that Is Enhanced by Cholesterol
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"Betulin Is a Potent Anti-Tumor Agen..." refers background in this paper
...DKO MEFs are resistant to drugs such as etoposide, staurosporine, UVC or actinomycin D, all targeting the Bcl-2 family regulated mitochondrial pathway [32]....
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"Betulin Is a Potent Anti-Tumor Agen..." refers background in this paper
...In principle, two main pathways can be distinguished, the extrinsic or death receptor pathway and the intrinsic or mitochondrial pathway with the latter being regulated by the Bcl-2 family of proteins [13]....
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"Betulin Is a Potent Anti-Tumor Agen..." refers background in this paper
...BE is a natural compound, which contains derivatives that have been shown to possess strong anti-tumor properties [7,33]....
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...BE is easily isolated and therefore plays an important role as raw material for the production of BetA and other biologically active compounds [7]....
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"Betulin Is a Potent Anti-Tumor Agen..." refers background in this paper
...BetA can be found in numerous different plants, but it can also be obtained by a simple 2 step reaction from its more abundantly available precursor molecule Betulin (BE) [3]....
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