Journal ArticleDOI
Beyond cholesterol: the atherogenic consequences of combined dyslipidemia.
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TLDR
The increasing prevalence of obesity and its accompanying cardiometabolic risk associated with this dyslipidemia that makes the article by Burns et al in this issue of The Journal so timely contribute to the understanding of why dyslipidsemia with LDL-C levels below the traditional cutoff for risk is still an LDL problem.About:
This article is published in The Journal of Pediatrics.The article was published on 2012-12-01. It has received 10 citations till now. The article focuses on the topics: Dyslipidemia.read more
Citations
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Journal ArticleDOI
Cardiovascular Risk Reduction in High-Risk Pediatric Patients: A Scientific Statement From the American Heart Association.
Sarah D. de Ferranti,Julia Steinberger,Rebecca K. Ameduri,Annette L. Baker,Holly C. Gooding,Aaron S. Kelly,Michele Mietus-Snyder,Mark Mitsnefes,Amy L. Peterson,Julie St-Pierre,Elaine M. Urbina,Justin P. Zachariah,Ali N. Zaidi +12 more
TL;DR: This scientific statement presents considerations for clinical management regarding the assessment and risk reduction of select pediatric populations at high risk for premature cardiovascular disease, including acquired arteriosclerosis or atherosclerosis.
Journal ArticleDOI
Children's Hospital Association consensus statements for comorbidities of childhood obesity.
Elizabeth Estrada,Ihuoma Eneli,Sarah Hampl,Michele Mietus-Snyder,Nazrat Mirza,Erinn T. Rhodes,Brooke Sweeney,Lydia Tinajero-Deck,Susan J. Woolford,Stephen J. Pont +9 more
TL;DR: App accessible, user-friendly clinical consensus statements are provided to facilitate the screening, interpretation of results, and early treatment for some of the most common childhood obesity comorbidities.
Journal ArticleDOI
Triglycerides-to-HDL ratio as a new marker of endothelial dysfunction in obese prepubertal children
Tommaso de Giorgis,M. Loredana Marcovecchio,Ilaria Di Giovanni,Cosimo Giannini,Valentina Chiavaroli,Francesco Chiarelli,Angelika Mohn +6 more
TL;DR: This study confirms the reliability of the TG:HDL-C ratio as a useful marker of cardiovascular risk and underline that the TG:[HDL]C ratio is directly related with early signs of vascular damage already present in prepubertal children.
Journal ArticleDOI
Lipoprotein particle number and size predict vascular structure and function better than traditional lipids in adolescents and young adults
Elaine M. Urbina,Connie E McCoy,Zhiqian Gao,Philip R. Khoury,Amy S. Shah,Lawrence M. Dolan,Thomas R. Kimball +6 more
TL;DR: Lipoprotein particle number and size are more strongly related to vascular structure and function than traditional lipid values, and NMR lipid measures may be a better indicator of risk for target organ damage thantraditional lipid measures in adolescents and young adults.
Journal ArticleDOI
Hypertriglyceridemia in Obese Children and Adolescents.
Mo Kyung Jung,Eun-Gyong Yoo +1 more
TL;DR: Results from genetic studies suggest that TG and TG-rich lipoproteins and, more specifically, remnant cholesterol are in the causal pathway of cardiovascular disease, but simultaneous measurement of all remnants has not yet been established, and plasma TG level can be used as a useful marker of remnant cholesterol.
References
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Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Scott M. Grundy,David W. Bilheimer,Alan Chait,Luther T. Clark,Margo A. Denke,Richard J. Havel,William R. Hazzard,Stephen B. Hulley,Donald B. Hunninghake,Robert A. Kreisberg,Penny M. Kris-Etherton,James M. McKenney,Michael A. Newman,Ernst J. Schaefer,Burton E. Sobel,Carolyn Somelofski,Milton C. Weinstein,H. Bryan Brewer,James I. Cleeman,Karen A. Donato,Nancy D. Ernst,Jeffrey M. Hoeg,Basil M. Rifkind,Jacques E. Rossouw,Christopher T. Sempos,Joanne M. Gallivan,Maureen N. Harris,Laurie Quint-Adler +27 more
TL;DR: Dairy therapy remains the first line of treatment of high blood cholesterol, and drug therapy is reserved for patients who are considered to be at high risk for CHD, and the fundamental approach to treatment is comparable.
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Detection, Evaluation, and Treatment of High Blood Cholesterol Education Program (NCEP) Expert Panel on Executive Summary of the Third Report of the National
William C. Taylor,Nigel Unwin +1 more
Journal ArticleDOI
Defining and Setting National Goals for Cardiovascular Health Promotion and Disease Reduction The American Heart Association’s Strategic Impact Goal Through 2020 and Beyond
Donald M. Lloyd-Jones,Yuling Hong,Darwin R. Labarthe,Dariush Mozaffarian,Lawrence J. Appel,Linda Van Horn,Kurt J. Greenlund,Stephen R. Daniels,Graham Nichol,Gordon F. Tomaselli,Donna K. Arnett,Gregg C. Fonarow,P. Michael Ho,Michael S. Lauer,Frederick A. Masoudi,Rose Marie Robertson,Véronique L. Roger,Lee H. Schwamm,Paul D. Sorlie,Clyde W. Yancy,Wayne D. Rosamond +20 more
TL;DR: This document details the procedures and recommendations of the Goals and Metrics Committee of the Strategic Planning Task Force of the American Heart Association, which developed the 2020 Impact Goals, to improve the cardiovascular health of all Americans by 20% while reducing deaths from cardiovascular diseases and stroke by 20%.
Journal ArticleDOI
Subendothelial Lipoprotein Retention as the Initiating Process in Atherosclerosis: Update and Therapeutic Implications
TL;DR: The finding that certain human populations of individuals who maintain lifelong low plasma levels of apolipoprotein B lipoproteins have an ≈90% decreased risk of coronary artery disease gives hope that further understanding of the pathogenesis of this leading killer could lead to its eradication.
Journal ArticleDOI
Lifetime Risks of Cardiovascular Disease
Jarett D. Berry,Alan R. Dyer,Xuan Cai,Daniel B. Garside,Hongyan Ning,Avis J. Thomas,Philip Greenland,Linda Van Horn,Russell P. Tracy,Donald M. Lloyd-Jones +9 more
TL;DR: Differences in risk-factor burden translate into marked differences in the lifetime risk of cardiovascular disease, and these differences are consistent across race and birth cohorts.
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Rationale for Use of Non–High-Density Lipoprotein Cholesterol Rather Than Low-Density Lipoprotein Cholesterol as a Tool for Lipoprotein Cholesterol Screening and Assessment of Risk and Therapy
Philip H. Frost,Richard J. Havel +1 more