Bibenzyl derivatives from the orchid Bulbophyllum protractum
TL;DR: In this paper, two new bibenzyl derivatives were isolated from the orchid Bulbophyllum protractum and designated bulbophyllin and bulbophilusidin.
About: This article is published in Phytochemistry.The article was published on 1997-01-01. It has received 31 citations till now. The article focuses on the topics: Bibenzyl.
Citations
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TL;DR: A phytochemical study of the whole plant of Bulbophyllum odoratissimum (J.E. Smith) Lindl (Orchidaceae) and cytotoxicity measurement of its isolated compounds have been carried out and all compounds, except for 9, have not been reported in this plant before.
66 citations
TL;DR: In this paper, the structures of amoenylin and isoamenylin were established as 4-hydroxy-3,4′-dihydroxy-5-methoxybibenzyl and 3, 4′-hydroxyl 3,4,5-trimethoxy bibenenzyl, respectively, mainly from spectral evidence.
65 citations
TL;DR: Thunalbene, a new stilbene derivative, was isolated from the orchid Thunia alba which also afforded six known stilbenoids: batatasin-III, lusianthridin, 3,7-dihydroxy-2,4-dimethoxyphenanthrene, 3.5methoxystilbenoid and flavanthrin this paper.
50 citations
TL;DR: In this paper, Reptanthrin and isoreptanthrin, two new dimeric phenanthrenes, were isolated from the orchid Bulbophyllum reptans which also afforded nine known stilbenoids, viz.
41 citations
TL;DR: One new bibenzyl, 7, and one new diarylheptanone, diobulbinone A (18), together with sixteen known compounds, 1–6 and 8–17, have been isolated form the rhizomes of Dioscorea bulbifera.
Abstract: One new bibenzyl, 7, and one new diarylheptanone, diobulbinone A (18), together with sixteen known compounds, 1-6 and 8-17, have been isolated form the rhizomes of Dioscorea bulbifera. Their structures were elucidated by NMR and MS analyses. Compound 7 showed high antioxidant capacity in FRAP assay and DPPH radical-scavenging activity.
32 citations
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TL;DR: All the bibenzyls caused leukemia cells to accumulate in mitosis at cytotoxic drug concentrations; however, a wide range of in vitro activity against the protein tubulin (the major component of the mitotic spindle) was observed.
Abstract: Further investigation of a CH2Cl2 fraction prepared from the South African tree Combretum caffrum for substances inhibitory to the murine P-388 lymphocytic leukemia (PS system) cell line has led to the isolation of two new bibenzyls, designated combretastatins B-3 and B-4, accompanied by the previously known bibenzyls 7, 8, and 9. The structure of each substance was ascertained by results of mass and nmr spectral analyses and confirmed by crystal structure determination (for 7) or synthesis. Combretastatins B-3 and B-4 gave PS ED50 values of 0.4 and 1.7 micrograms/ml, respectively, and bibenzyls 7, 8, and 9 were comparably cell growth inhibitory against the PS cell line with ED50 results of 1.7, 2.5, and 0.25 ug/ml, respectively. All the bibenzyls caused leukemia cells to accumulate in mitosis at cytotoxic drug concentrations; however, a wide range of in vitro activity against the protein tubulin (the major component of the mitotic spindle) was observed.
79 citations
TL;DR: 2,7-Dihydroxy-4-methoxy-9,10-dihydrophenanthrene was isolated and identified from the whole plant of Coelogyne ochracea and C. elata.
77 citations
TL;DR: Three new substituted bibenzyls (1,2-diarylethanes) aloifol I and aloIFol II and a new substituted 9,10-dihydrophenanthrene, 6-O-methylcoelonin in addition to batatasin III, coel onin and gigantol have been isolated and characterized.
70 citations
TL;DR: Lusianthrin and lusian-thridin, two new stilbenoids, were isolated from the orchid Lusia indivisa.
66 citations
TL;DR: Flavanthrin, the first dimeric 9,10-dihydrophenanthrene derivative, was isolated from the orchid Eria flava which also yielded the previously reported 9, 10-dibhrenanthrene coelonin this paper.
54 citations