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Bidirectional Associations Between Clinically Relevant Depression or Anxiety and COPD: A Systematic Review and Meta-analysis

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TLDR
Depression and anxiety adversely affect prognosis in COPD, conferring an increased risk of exacerbation and possibly death, and bidirectional associations suggest potential usefulness of screening for these disease combinations to direct timely therapeutic intervention.
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This article is published in Chest.The article was published on 2013-09-01. It has received 245 citations till now. The article focuses on the topics: Anxiety & Exacerbation.

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Citations
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Chronic obstructive pulmonary disease.

TL;DR: In this paper, the authors investigated the mechanisms underlying chronic obstructive pulmonary disease (COPD), which is associated with chronic inflammation that is usually corticosteroid resistant, and accelerated ageing of the lungs and an abnormal repair mechanism driven by oxidative stress.
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Depression and anxiety in patients with COPD

TL;DR: There are some promising findings regarding pulmonary rehabilitation, psychological therapy and the collaborative care model in reducing depression and anxiety symptoms in patients with COPD, but these findings are limited by short-term follow-up periods and further work is required to examine the efficacy of these interventions in randomised controlled trials with larger samples and long-termFollow-up.
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epidemiology and clinical impact of major comorbidities in patients with COPD

TL;DR: This review will highlight the importance of comorbidity identification and management in the practice of caring for patients with COPD and emphasize the clinical impact upon prognosis and management considerations.
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Depression and Anxiety as Risk Factors for Morbidity and Mortality After Organ Transplantation: A Systematic Review and Meta-Analysis.

TL;DR: Depression increases risk for posttransplant mortality; the depression-graft loss association suggests that linkages with morbidities deserve greater attention.
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Happiness and Health.

TL;DR: Interventions have yet to demonstrate substantial, sustained improvements in subjective well-being or direct impact on physical health outcomes, but this field shows great potential, with the promise of establishing a favorable effect on population health.
References
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Journal ArticleDOI

Bias in meta-analysis detected by a simple, graphical test

TL;DR: Funnel plots, plots of the trials' effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials.
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Meta-Analysis in Clinical Trials*

TL;DR: This paper examines eight published reviews each reporting results from several related trials in order to evaluate the efficacy of a certain treatment for a specified medical condition and suggests a simple noniterative procedure for characterizing the distribution of treatment effects in a series of studies.
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Quantifying heterogeneity in a meta‐analysis

TL;DR: It is concluded that H and I2, which can usually be calculated for published meta-analyses, are particularly useful summaries of the impact of heterogeneity, and one or both should be presented in publishedMeta-an analyses in preference to the test for heterogeneity.
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