Bioavailability of bioactive food compounds: a challenging journey to bioefficacy
Citations
492 citations
Cites background from "Bioavailability of bioactive food c..."
...The bioavailability of β-carotene from plant sources is generally low (10- 65 %), due to resistance of carotene–protein complexes, fibres and the plant cell walls to digestion and degradation to achieve adequate release of carotenoids (Rein et al., 2013)....
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347 citations
Cites background from "Bioavailability of bioactive food c..."
...One of the important factors of bioavailability is the fat solubility of the ingested flavonols [10]....
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...Bioavailability from a nutritional perspective is defined as the extent of digestion, absorption, metabolism, and excretion of a compound after the ingestion of food [10]....
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...bioavailability of bioactive compounds is an essential step in determining the potential mechanisms of action of flavonols [10]....
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344 citations
Cites background from "Bioavailability of bioactive food c..."
...molecule and affect its eventual rate and extent of absorption [33,34]....
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...These studies might be interpreted to suggest only small level of bioavailability; however, it is important to realise that betacyanins are unlikely to be exclusively eliminated via the renal pathway [36] Indeed, the use of urinary excretion as a sole indicator of bioavailability has received criticism because it does not account for the biliary and circulatory clearance of compounds, thus underestimating true bioavailability [33]....
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..., first pass metabolism, interactions with gut microflora and protease enzyme degradation) have a significant influence on the concentration of the nutrient that eventually reaches the circulation [33,34]....
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337 citations
Cites background from "Bioavailability of bioactive food c..."
...Interactions with other food components, such as proteins, play also a role (Bohn et al., 2015; Aedín Cassidy &Minihane, 2017; Rein et al., 2013)....
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References
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