Journal ArticleDOI
Biodegradable polymers as biomaterials
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This review summarizes the main advances published over the last 15 years, outlining the synthesis, biodegradability and biomedical applications ofBiodegradable synthetic and natural polymers.About:
This article is published in Progress in Polymer Science.The article was published on 2007-08-01. It has received 3801 citations till now. The article focuses on the topics: Biomaterial & Biodegradable polymer.read more
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Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier
TL;DR: This manuscript describes the various fabrication techniques for these devices and the factors affecting their degradation and drug release.
Journal ArticleDOI
The return of a forgotten polymer—Polycaprolactone in the 21st century
TL;DR: Polycaprolactone (PCL) was used in the biomaterials field and a number of drug-delivery devices for up to 3-4 years.
Journal ArticleDOI
Microfibrillated cellulose and new nanocomposite materials: a review
Istvan Siró,David Plackett +1 more
TL;DR: In this article, a review summarizes progress in nanocellulose preparation with a particular focus on microfibrillated cellulose and also discusses recent developments in bio-nanocomposite fabrication based on nanocells.
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Biomedical Applications of Biodegradable Polymers
TL;DR: This review summarizes the most recent advances in the field over the past 4 years, specifically highlighting new and interesting discoveries in tissue engineering and drug delivery applications.
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Physical and mechanical properties of PLA, and their functions in widespread applications - A comprehensive review.
TL;DR: The main purpose of this review is to elaborate the mechanical and physical properties that affect PLA stability, processability, degradation, PLA-other polymers immiscibility, aging and recyclability, and therefore its potential suitability to fulfill specific application requirements.
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Journal ArticleDOI
Silk-based biomaterials
Gregory H. Altman,Frank Diaz,Caroline M. Jakuba,Tara Calabro,Rebecca L. Horan,Jingsong Chen,Helen H. Lu,John C. Richmond,David L. Kaplan +8 more
TL;DR: Studies with well-defined silkworm silk fibers and films suggest that the core silk fibroin fibers exhibit comparable biocompatibility in vitro and in vivo with other commonly used biomaterials such as polylactic acid and collagen.
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Synthetic biodegradable polymers as orthopedic devices.
John Middleton,Arthur J. Tipton +1 more
TL;DR: In this paper, the authors focus on properties of biodegradable polymers which make them ideally suited for orthopedic applications where a permanent implant is not desired, and an overview of biocompatibility and approved devices of particular interest in orthopedics are also covered.
Journal ArticleDOI
Collagens—structure, function, and biosynthesis
TL;DR: The importance of different collagen types not only for the understanding of collagen-related diseases, but also as a basis for the therapeutical use of members of this protein family discussed in other chapters of this issue is indicated.
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Application of chitosan-based polysaccharide biomaterials in cartilage tissue engineering : a review
TL;DR: Some biomaterials, which have been suggested to promote chondrogenesis and to have potentials for tissue engineering of articular cartilage, are reviewed and a new biomaterial, a chitosan-based polysaccharide hydrogel, is introduced and discussed in terms of the biocompatibility with chondrocytes.
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Polyionic hydrocolloids for the intestinal delivery of protein drugs: alginate and chitosan--a review.
Meera George,T. Emilia Abraham +1 more
TL;DR: Alginate, being an anionic polymer with carboxyl end groups, is a good mucoadhesive agent and cross-linked alginate has more capacity to retain the entrapped drugs and mixing of alginates with other polymers such as neutral gums, chitosan, and eudragit have been found to solve the problem of drug leaching.