Biofilms in Otolaryngology

TLDR: The main goal of this review is to evaluate and discuss in detail some of the recent findings in biofilm-related otolaryngologic states.

Abstract: Biofilms have been shown to play an important role in otolaryngologic disorders. Recent advances have demonstrated that there are different bacterial species within the biofilms in different disease states. Since the recognition that chronic otolaryngologic infections are associated with biofilms, new treatment strategies with new agents have been trying to be developed for antibiotic-resistant bacterial biofilms. It has been well known that inadequate doses of antibiotic treatment can trigger biofilm formation and can lead to chronic infections. In fact, to diagnose, treat and prevent biofilm-related illnesses, different strategies are required. Determining the bacterial genetics of biofilm formation and the interaction between host and bacteria will provide substantial targets for biofilm drug therapies. The main goal of this review is to evaluate and discuss in detail some of the recent findings in biofilms-related otolaryngologic states. (JAREM 2013; 3: 1-4)